Clinical trial comparing nicotine replacement therapy (NRT) plus brief counselling, brief counselling alone, and minimal intervention on smoking cessation in hospital inpatients

Clinical trial comparing nicotine replacement therapy (NRT) plus brief counselling, brief counselling alone, and minimal intervention on smoking cessation in hospital inpatients
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DOI:
10.1136/thorax.58.6.484
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发表时间:
2003-06-01
期刊:
影响因子:
10
通讯作者:
Britton, J
Britton, J
中科院分区:
医学1区
文献类型:
--
作者:
Molyneux, A;Lewis, S;Britton, J

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背景:指南建议在所有临床环境中向所有愿意尝试戒烟的吸烟者提供戒烟干预。由于对住院吸烟者提供常规行为咨询和尼古丁替代疗法(NRT)的有效性尚未得到证实,因此在住院患者中进行了一项随机对照试验,将这些干预措施与单独的咨询或最低限度的干预进行比较。方法:入院时仍在吸烟的内科和外科住院患者被随机分为常规护理(入院时没有额外建议)、单独咨询(20分钟干预+书面材料)或NRT+咨询(咨询干预+6周的NRT疗程)。持续和时点戒烟(通过呼出一氧化碳确认)
Background: Guidelines recommend that smoking cessation interventions are offered in all clinical settings to all smokers willing to make a quit attempt. Since the effectiveness of routine provision of behavioural counselling and nicotine replacement therapy (NRT) to smokers admitted to hospital has not been established, a randomised controlled trial of these interventions given together compared with counselling alone or minimal intervention was performed in hospital inpatients.Methods: Medical and surgical inpatients who were current smokers at the time of admission were randomised to receive either usual care (no additional advice at admission), counselling alone (20 minute intervention with written materials), or NRT plus counselling (counselling intervention with a 6 week course of NRT). Continuous and point prevalence abstinence from smoking (validated by exhaled carbon monoxide