A bound on the energy resolution required for quantitative SPECT.
A bound on the energy resolution required for quantitative SPECT.
复制标题
定量 SPECT 所需能量分辨率的界限。
DOI：
10.1118/1.597697
复制
发表时间：
1996
期刊：
影响因子：
3.8
通讯作者：
Hasegawa,BH
中科院分区：
文献类型：
--
作者：
Heanue,JA;Brown,JK;Tang,HR;Hasegawa,BH
散射辐射是限制单光子发射计算机断层扫描（SPECT）定量测量准确性的几种物理扰动之一。探测器能量分辨率的提高导致散射计数的减少和SPECT测量的定量准确性的相应提高。在这项研究中，模拟SPECT投影的一个简单的心肌灌注体模被用来研究探测器的能量分辨率的数据的影响。体模由半径为15 cm的充水圆柱体内的放射性核素球壳组成。每个投影包含3× 105个计数。结果表明，在这种情况下，与光子统计引起的不确定性相比，3-4 keV的全宽半最大能量分辨率足以使散射引起的误差微不足道。进一步的模拟验证，因为较小的物体产生较少的散射，它们可以准确地成像，降低能量分辨率。这些结果在设计利用固态探测器和低噪声电子器件来实现改进的能量分辨率的原型系统时非常有用。
Scattered radiation is one of several physical perturbations that limit the accuracy of quantitative measurements in single‐photon emission computed tomography (SPECT). Improvement in detector energy resolution leads to a reduction of scatter counts and a corresponding improvement in the quantitative accuracy of the SPECT measurement. In this study, simulated SPECT projections of a simple myocardial perfusion phantom were used to investigate the effect of detector energy resolution on the data. The phantom consists of a spherical shell of radionuclide within a 15 cm radius water‐filled cylinder. Each projection contains on the order of 3×105counts. The results demonstrate that a full‐width, half‐maximum energy resolution of 3–4 keV is sufficient to render the error due to scatter insignificant compared to the uncertainty due to photon statistics in this case. Further simulations verify that because smaller objects produce less scatter, they can be imaged accurately with degraded energy resolution. These results are useful when designing prototype systems that utilize solid‐state detectors and low‐noise electronics to achieve improved energy resolution.