Central gustatory lesions: II. Effects on sodium appetite, taste aversion learning, and feeding behaviors.
Central gustatory lesions: II. Effects on sodium appetite, taste aversion learning, and feeding behaviors.
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DOI：
10.1037//0735-7044.105.6.944
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发表时间：
1991-12
影响因子：
1.9
通讯作者：
F. Flynn;H. Grill;J. Schulkin;R. Norgren
中科院分区：
文献类型：
--
作者：
F. Flynn;H. Grill;J. Schulkin;R. Norgren
Intake and taste reactivity tests were used to determine the effects of bilateral lesions of the gustatory portions of the nucleus of the solitary tract (NST), the parabrachial nucleus (PBN), and the ventral posteromedial nucleus of the thalamus (VPMpc) on several complex ingestive behaviors. In the 1st experiment, lesions of the PBN and the NST blocked, and VPMpc lesions impaired, the behavioral expression of salt appetite. In the 2nd experiment, alanine was paired with injections of LiCl. Control rats as well as rats with NST and VPMpc lesions acquired the taste aversion, but rats with PBN lesions did not. In the 3rd experiment, all animals increased their food intake after injections of 2 U/kg insulin and 250 mg/kg 2-deoxy-D-glucose, and their food intake was suppressed after nutritive stomach loads.
