Physical activity and risk of type 2 diabetes among Native Hawaiians, Japanese Americans, and Caucasians: the Multiethnic Cohort.
Physical activity and risk of type 2 diabetes among Native Hawaiians, Japanese Americans, and Caucasians: the Multiethnic Cohort.
复制标题
夏威夷原住民、日裔美国人和白种人的体力活动和 2 型糖尿病风险：多种族队列。
DOI：
10.1123/jpah.9.5.634
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发表时间：
2012
影响因子：
3.1
通讯作者：
Maskarinec,Gertraud
中科院分区：
文献类型：
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作者：
Steinbrecher,Astrid;Erber,Eva;Grandinetti,Andrew;Nigg,Claudio;Kolonel,LaurenceN;Maskarinec,Gertraud
缺乏体力活动是糖尿病的既定危险因素；然而，对于不同糖尿病风险的种族之间的这种联系，我们知之甚少。因此，我们在多种族队列的夏威夷部分评估了体力活动与糖尿病和潜在影响调整之间的关联。方法参与者年龄在45岁到75岁之间，通过完成一份关于人口统计学、饮食和自我报告的每周剧烈运动、剧烈工作和适度活动时间的问卷进行登记。在74913名参与者中(39%的高加索人，14%的夏威夷原住民，47%的日裔美国人)，8561例糖尿病事件是通过自我报告、药物调查问卷和健康计划联系确定的。结果参加剧烈运动与糖尿病风险呈负相关，女性和男性的危险比(HR)分别为0.67(95%CI：0.57~0.79)和0.80(95%CI：0.72~0.88)。在分层分析中，这种反向关联在不同种族之间是一致的。剧烈运动与糖尿病的反向关联仅限于男性，而适度运动的有益影响仅在高加索人中观察到。结论这些发现支持高强度体力活动和特定种族的指南在糖尿病预防中的作用。
BackgroundPhysical inactivity is an established risk factor for diabetes; however, little is known about this association across ethnic groups with different diabetes risk. Therefore, we evaluated the association between physical activity and diabetes and potential effect modification by ethnicity in the Hawaii component of the Multiethnic Cohort.MethodsParticipants, aged 45 to 75 years, were enrolled by completing a questionnaire on demographics, diet, and self-reported weekly hours of strenuous sports, vigorous work, and moderate activity. Among the 74,913 participants (39% Caucasian, 14% Native Hawaiian, 47% Japanese American), 8561 incident diabetes cases were identified by self-report, a medication questionnaire, and through health plan linkages. Cox regression was applied to estimate hazard ratios (HR) and 95% confidence intervals (95%CI) while adjusting for known confounders.ResultsEngaging in strenuous sports was inversely related to diabetes risk with HRs (4+ hours/week vs. never) of 0.67 (95%CI: 0.57–0.79) in women and 0.80 (95%CI: 0.72–0.88) in men. In stratified analyses, the inverse association was consistent across ethnic groups. The inverse association of vigorous work with diabetes was limited to men, while beneficial effects of moderate activity were observed only in Caucasians.ConclusionsThese findings support a role of high-intensity physical activity and ethnic-specific guidelines in diabetes prevention.