Narrow band imaging of nasopharynx to identify specific features for possible detection of early nasopharyngeal carcinoma
Narrow band imaging of nasopharynx to identify specific features for possible detection of early nasopharyngeal carcinoma
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DOI：
10.1002/hed.23705
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发表时间：
2015-08-01
影响因子：
2.9
通讯作者：
Loh, Kwok Seng
中科院分区：
文献类型：
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作者：
Madana, J.;Lim, Chwee Ming;Loh, Kwok Seng
背景正常及早期鼻咽癌的窄带成像（NBI）特征尚不清楚。本研究的主要目的是确定NBI功能在鼻咽部的早期NPC.MethodsWe检测进行了前瞻性队列研究的53例患者谁接受NBI内镜描述其具体features.ResultsAmong 19例正常人，常见的NBI功能是离散的棕色斑点（100%）和规则的多边形滤泡模式的鼻咽粘膜（90%）。15例鼻咽癌患者鼻咽部正常多角形滤泡结构消失（100%），集中的棕色斑点（93%）和淡粉红色区域（80%）。在19鼻咽癌放疗后患者，共同的特点是补丁的强烈棕绿色斑点（100%），损失多边形滤泡模式的鼻咽粘膜（95%），离散微血管分支（95%.ConclusionThere是可辨别的NBI功能之间的正常粘膜和外生性鼻咽癌肿块。这可以形成使用NBI检测早期NPC的前瞻性筛查计划的基础。(c)2014 Wiley Periodicals，Inc.头颈部37：1096-1101，2015
BackgroundNarrow band imaging (NBI) features of normal and early nasopharyngeal carcinoma (NPC) have not been clearly described. The main purpose of this study was to define NBI features in the nasopharynx in the detection of early NPC.MethodsWe conducted a prospective cohort study of 53 patients who underwent NBI endoscopy to describe its specific features.ResultsAmong 19 normal patients, common NBI features were discrete brown spots (100%) and regular polygonal follicular pattern of nasopharyngeal mucosa (90%). The features of 15 patients with NPC were loss of normal polygonal follicular architecture of nasopharynx (100%), concentrated brown spots (93%), and pale pink areas (80%). In the 19 post-NPC radiation patients, common features were patches of intense brown-green spots (100%), loss of polygonal follicular pattern of nasopharyngeal mucosa (95%), and discrete microvasculature branches (95%).ConclusionThere are discernible NBI features between normal mucosa and an exophytic NPC mass. This can form the basis of a prospective screening program to detect early NPC using NBI. (c) 2014 Wiley Periodicals, Inc. Head Neck37: 1096-1101, 2015