Radiotherapy setup displacements in breast cancer patients: 3D surface imaging experience
Radiotherapy setup displacements in breast cancer patients: 3D surface imaging experience
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DOI：
10.1016/j.rpor.7017.12.007
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发表时间：
2018-01-01
影响因子：
1.2
通讯作者：
Bonnarens, Emmanuel
中科院分区：
文献类型：
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作者：
Sa, Ana Cravo;Fermento, Ana;Bonnarens, Emmanuel
目的：在这项研究中，我们打算比较两种不同的设置程序为女性乳腺癌patients.Background：在放射治疗成像提供了一个精确的定位肿瘤，提高治疗的准确性在乳腺癌。材料与方法：选择20例接受全乳放疗（WBRT）的乳腺癌患者。患者被分为两组，每组10人。第一组（G1）通过纹身定位，然后借助AlignRT（Vision RT，伦敦，英国）调整患者体位。第二组（G2），患者仅通过纹身定位。对于两组，分析前15个部分，制作每日千伏（kV）锥形束计算机断层扫描（CBCT）图像，然后分析旋转和平移位移，以及后面的系统（X '）和随机（a）误差。两组CBCT位移的比较显示平移左右（LR）方向的统计学显著差异（p= 0.03），考虑到使用AlignRT系统的手术具有较小的侧向位移。系统误差（X '）和随机误差（α）的结果表明，对于平移位移，仅通过纹身定位的组（G2）与借助AlignRT定位的组（G1）相比显示出更高的误差值。结论：AlignRT可以帮助乳腺癌患者定位;但是，它应该与另一种成像方法一起使用。(C)2018年大波兰癌症中心。由Elsevier Sp. z o.o.发布All rights reserved.
Aim: In this study, we intend to compare two different setup procedures for female breast cancer patients.Background: Imaging in radiotherapy provides a precise localization of the tumour, increasing the accuracy of the treatment delivery in breast cancer. Materials and methods: Twenty breast cancer patients who underwent whole breast radiotherapy (WBRT) were selected for this study. Patients were divided into two groups of ten. Group one (G1) was positioned by tattoos and then the patient positioning was adjusted with the aid of AlignRT (Vision RT, London, UK). In group two (G2), patients were positioned only by tattoos. For both groups, the first 15 fractions were analyzed, a daily kilovoltage (kV) cone beam computed tomography (CBCT) image was made and then the rotational and translational displacements and, posteriorly, the systematic (X') and random (a) errors were analyzed.Results: The comparison of CBCT displacements for the two groups showed a statistically significant difference in the translational left-right (LR) direction (p= 0.03), considering that the procedure with AlignRT system has smaller lateral displacements. The results of systematic (X') and random (a) errors showed that for translational displacements the group positioned only by tattoos (G2) demonstrated higher values of errors when compared with the group positioned with the aid of AlignRT (G1).Conclusions: AlignRT could help the positioning of breast cancer patients; however, it should be used with another imaging method. (C) 2018 Greater Poland Cancer Centre. Published by Elsevier Sp. z o.o. All rights reserved.