Cloning and pharmacological characterization of the dog P2X7 receptor

Cloning and pharmacological characterization of the dog P2X7 receptor
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狗P2X7受体的克隆和药理学表征

DOI:
10.1111/j.1476-5381.2009.00425.x
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发表时间:
2009
影响因子:
7.3
通讯作者:
Anton D. Michel
Anton D. Michel
中科院分区:
医学2区
文献类型:
--
作者:
S. Roman;FS Cusdin;Elena Fonfria;J. A. Goodwin;J. Reeves;SC Lappin;L. J. Chambers;Daryl S. Walter;W. C. Clay;Anton D. Michel

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背景和目的: 人类和啮齿动物的P2X7受体对拮抗剂的敏感性不同。在这项研究中,我们克隆并鉴定了狗的P2X7受体,以确定它的拮抗剂敏感性是否更接近于人类或啮齿动物的同源物。
Background and purpose:  Human and rodent P2X7 receptors exhibit differences in their sensitivity to antagonists. In this study we have cloned and characterized the dog P2X7 receptor to determine if its antagonist sensitivity more closely resembles the human or rodent orthologues.
DOI: 10.1152/ajpcell.00532.2004
发表时间: 2005
期刊: American journal of physiology. Cell physiology
影响因子: --
作者:
Liang,Lihua;Schwiebert,ErikM
通讯作者: Schwiebert,ErikM