NON-VIREMIC TRANSMISSION OF TICK-BORNE ENCEPHALITIS-VIRUS - A MECHANISM FOR ARBOVIRUS SURVIVAL IN NATURE
NON-VIREMIC TRANSMISSION OF TICK-BORNE ENCEPHALITIS-VIRUS - A MECHANISM FOR ARBOVIRUS SURVIVAL IN NATURE
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DOI：
10.1007/bf01923553
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发表时间：
1993-09-15
期刊：
影响因子：
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通讯作者：
SABO, A
中科院分区：
文献类型：
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作者：
LABUDA, M;NUTTALL, PA;SABO, A
节肢动物传播的病毒（虫媒病毒）的载体通过进食受感染动物的病毒血症血液而被感染。这一理论是基于通过注射器接种对脊椎动物宿主进行人工感染的传播研究。为了重现病毒传播的自然条件，欧洲最重要的虫媒病毒--蜱传脑炎病毒的感染和未感染载体（蜱）被允许一起取食未感染的野生脊椎动物宿主。最大数量的感染蜱来自病毒血症水平不可检测或非常低的易感宿主种属。结果表明，“非病毒血症传播”是某些虫媒病毒在自然界中生存的重要机制。
The vectors of arthropod-borne viruses (arboviruses) become infected by feeding on the viraemic blood of an infected animal. This theory is based on transmission studies involving artificial infection of vertebrate hosts by syringe inoculation. To reproduce natural conditions of virus transmission, infected and uninfected vectors (ticks) of tick-borne encephalitis virus, the most important arbovirus in Europe, were allowed to feed together on uninfected wild vertebrate hosts. The greatest numbers of infected ticks were obtained from susceptible host species that had undetectable or very low levels of viraemia. The results suggest that 'nonviremic transmission' is an important mechanism for the survival of certain arboviruses in nature.