BODY-FAT DISTRIBUTION AND OSTEOARTHRITIS
BODY-FAT DISTRIBUTION AND OSTEOARTHRITIS
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DOI：
10.1093/oxfordjournals.aje.a115711
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发表时间：
1990-10-01
影响因子：
5
通讯作者：
MUELLER, WH
中科院分区：
文献类型：
--
作者：
DAVIS, MA;NEUHAUS, JM;MUELLER, WH
使用1960-1962年美国健康检查调查I（HES I）和1971-1975年第一次全国健康和营养检查调查I（NHANES I）的数据研究了体脂分布与单部位和联合部位骨关节炎的相关性。该研究包括来自HES I的1，636名年龄在35-79岁之间的成年人，他们接受了手足X光片和四项人体脂肪分布测量-肩胛下和三头肌皮褶厚度、腰围和座宽，以及来自NHANES I的3，885名年龄在45-74岁之间的成年人，他们接受了膝关节X光片和肩胛下和三头肌皮褶厚度测量。性别特异性数据，调整年龄，种族和体重指数进行了分析，使用多分类逻辑回归。体重指数与膝关节骨关节炎和手足骨关节炎呈正相关。外周体围模式与手脚联合部位骨关节炎相关;然而，体脂分布与膝骨关节炎或仅与手脚骨关节炎的相关性并不一致。这些发现表明，在先前的研究中观察到的与心血管和胆囊疾病以及糖尿病相关的中心体脂肪模式与手，脚或膝盖的骨关节炎无关。
The association of body fat distribution with single and combined site osteoarthritis was investigated using data from the US Health Examination Survey I, 1960-1962 (HES I) and the first National Health and Nutritional Examination Survey I, 1971-1975 (NHANES I). The study included 1,636 adults aged 35-79 years from HES I with hands and feet radiographs and four anthropometric fat distribution measures-subscapular and triceps skinfolds, waist girth, and seat breadth.sbd.and 3,885 adults aged 45-74 from NHANES I with knee radiographs and subscapular and triceps skinfold measures. Sex-specific data, adjusted for age, race, and body mass index were analyzed using polychotomous logistic regression. There was a positive association of body mass index with knee osteoarthritis and with combined hands and feet osteoarthritis. A peripheral body girth pattern was associated with combined site osteoarthritis of the hands and feet; however, there was no consistent pattern of association of body fat distribution with knee osteoarthritis nor with osteoarthritis of the hands or feet only. These findings suggest that the central body fat pattern observed in previous studies to be associated with cardiovascular and gallbladder disease, and with diabetes, is not associated with osteoarthritis of the hands, feet, or knees.