Effects of Short-term Exposure to Ambient Particulate Matter on the Lung Function of School Children in Dhaka, Bangladesh
Effects of Short-term Exposure to Ambient Particulate Matter on the Lung Function of School Children in Dhaka, Bangladesh
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DOI：
10.1097/ede.0000000000001012
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发表时间：
2019-07-01
期刊：
影响因子：
5.4
通讯作者：
Watanabe, Chiho
中科院分区：
文献类型：
--
作者：
Tasmin, Saira;Ng, Chris Fook Sheng;Watanabe, Chiho
背景：大气颗粒物污染可能对儿童的肺功能产生不利影响。然而，这种关联的证据仍然稀少，在亚洲，尽管该地区的疾病负担最大，由于空气pollutation.Objectives：调查短期暴露于环境颗粒物（PM）对学龄儿童的肺功能在达卡市，孟加拉国的影响。这种关联的可能的季节性修改也examined.Methods：315名学童谁是9-16岁的面板被招募从三所学校和周围的达卡。在2013年的凉爽和温暖季节，使用肺功能测定法对肺功能进行了评估，每名儿童进行了6次测量。每天的PM数据来自附近的空气监测站。线性混合效应模型用于检查关联。结果：肺功能参数与PM2.5呈负相关，峰值呼气流量（PEF）和1秒内用力呼气量（FEV 1）随着PM2.5的增加而降低。前一天PM2.5增加20 μ g/m3时，PEF和FEV 1与个人中位数的百分比偏差分别为-4.19%（95%置信区间（CI）：-5.72，-2.66）和-2.05%（95% CI：-2.92，-1.18）。PM10的结果不太一致。PM对肺功能的估计影响一般在温暖的season.Conclusions：短期暴露于PM与生活在高污染环境中的儿童肺功能较差，这些不利的PM影响的强度随季节而变化。
Background: Ambient particulate pollution may adversely affect children's lung function. However, evidence on this association remains scarce in Asia despite this region having the greatest burden of disease due to air pollution.Objectives: To investigate the effect of short-term exposure to ambient particulate matter (PM) on the lung function of school children in Dhaka city, Bangladesh. The possible seasonal modification of this association was also examined.Methods: A panel of 315 school children who were 9-16 years of age were recruited from three schools in and around Dhaka. Lung function was assessed using a spirometry test during the cool and warm seasons in 2013, yielding six measurements per child. Daily PM data were retrieved from nearby air monitoring stations. Linear mixed effects models were used to examine associations. Seasonal modification was examined by stratification.Results: An inverse association was observed for the lung function parameters with PM2.5; peak expiratory flow (PEF) and forced expiratory volume within 1 second (FEV1) decreased with increasing PM2.5. The percent deviation from the personal median was -4.19% [95% confidence interval (CI): -5.72, -2.66] for PEF and -2.05% (95% CI: -2.92, -1.18) for FEV1 for a 20 mu g/m(3) increase in PM2.5 on the previous day. Results for PM10 were less consistent. The estimated effects of PM on lung functions were generally greater in the warm season.Conclusions: Short-term exposure to PM is associated with worse lung function in children living in highly polluted settings, with the strength of these adverse PM effects varying by season.