Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe
Lymphocytes rearrange, edit and revise their antigen receptors to be useful yet safe
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DOI：
10.1016/s0167-5699(00)01734-5
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发表时间：
2000-11-01
期刊：
影响因子：
--
通讯作者：
McMahan, CJ
中科院分区：
文献类型：
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作者：
Fink, PJ;McMahan, CJ
Pamela Fink和Catherine McMahan讨论了B和T细胞如何测试有用的抗原受体并排除潜在的有害受体，特别关注T细胞受体的修正，这是一种新描述的成熟T细胞维持自身耐受的机制。
Pamela Fink and Catherine McMahan discuss how B and T cells test for useful antigen receptors and weed out potentially harmful ones, with special attention paid to T-cell receptor revision, a newly described mechanism by which mature T cells can maintain self tolerance.