Gestational diabetes prevention and treatment: a protocol for developing core outcome sets
Gestational diabetes prevention and treatment: a protocol for developing core outcome sets
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DOI：
10.1136/bmjopen-2019-030574
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发表时间：
2019-11-01
期刊：
影响因子：
2.9
通讯作者：
Fhelelboom, Narjes
中科院分区：
文献类型：
--
作者：
Egan, Aoife Maria;Dunne, Fidelma P.;Fhelelboom, Narjes
前言选择性报告偏倚、试验间选择结果的不一致性以及妇女选择结果的不相关性限制了妊娠期糖尿病（GDM）预防和治疗研究的效率和价值。解决这些挑战的一种方法是开发核心结果集（COSs.Methods和分析）这篇手稿的目的是提出一个研究方案，以开发用于GDM预防和治疗的COSs。这是一个三阶段的项目，包括（1）文献的系统性综述，以创建两个已在试验中报告的结局列表，以及预防和治疗GDM干预试验的系统性综述，（2）三轮，与主要利益相关者进行基于网络的电子德尔菲调查，以确定这些结果的优先次序;（3）协商一致的会议，以解决任何剩余的分歧，并商定两个COS。
Introduction Selective reporting bias, inconsistency in the chosen outcomes between trials and irrelevance of the chosen outcomes for women, limit the efficiency and value of research for prevention and treatment of gestational diabetes mellitus (GDM). One way to address these challenges is to develop core outcome sets (COSs).Methods and analysis The aim of this manuscript is to present a protocol for a study to develop COSs for GDM prevention and treatment. This is a three-phase project consisting of (1) a systematic review of the literature to create two lists of outcomes that have been reported in trials and systematic reviews of trials of interventions for the prevention and treatment of GDM, (2) a three-round, web-based e-Delphi survey with key stakeholders to prioritise these outcomes and (3) a consensus meeting to resolve any remaining disagreements and to agree on two COSs.