Persistence of yellow fever vaccine RNA in urine
Persistence of yellow fever vaccine RNA in urine
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DOI：
10.1016/j.vaccine.2011.02.075
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发表时间：
2011-04-18
期刊：
影响因子：
5.5
通讯作者：
Hayes, Edward B.
中科院分区：
文献类型：
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作者：
Martinez, Miguel J.;Vilella, Anna;Hayes, Edward B.
为了评估17D黄热病疫苗的可能持久性，我们在接种后一年内的不同时间检测了44名健康黄热病疫苗接种者的尿液样本。两名疫苗接种者的尿液样本可检测到黄热病病毒RNA。一份样本的接种后时间报告为21天，另一份样本报告为198天。这些结果表明，黄热病疫苗病毒可能在某些人接种疫苗后持续至少6个月。(C)2011爱思唯尔有限公司版权所有。
To evaluate possible persistence of 17D yellow fever vaccine, we tested urine samples from 44 healthy recipients of yellow fever vaccine at varying times up to one year after vaccination. Urine samples from two vaccine recipients had detectable yellow fever virus RNA. The time since vaccination was reported as 21 days for one sample and 198 days for the other sample. These results suggest that yellow fever vaccine virus might persist for at least 6 months after vaccination in some people. (C) 2011 Elsevier Ltd. All rights reserved.