EARLY TRIGEMINAL EVOKED-POTENTIALS IN TUMORS OF THE BASE OF THE SKULL AND TRIGEMINAL NEURALGIA
EARLY TRIGEMINAL EVOKED-POTENTIALS IN TUMORS OF THE BASE OF THE SKULL AND TRIGEMINAL NEURALGIA
复制标题
DOI：
10.1016/0168-5597(88)90069-x
复制
发表时间：
1988-03-01
期刊：
影响因子：
--
通讯作者：
FAVALE, E
中科院分区：
文献类型：
--
作者：
LEANDRI, M;PARODI, CI;FAVALE, E
对23例颅底肿瘤（鞍旁区和桥小脑角）和38例原发性三叉神经痛患者进行了眶下神经（W_1、W_2、W_3）刺激诱发的早期头皮反应的研究。健康和患侧之间的传导时间的差异进行了评估，并面对从30名正常志愿者获得的数据。在所有有三叉神经区临床体征的颅底肿瘤患者和12例无此类体征的患者中，发现了反应的改变。在鞍旁区肿瘤的病例中，通常的改变模式是W2和W3的平行受累（两者均缺失或延迟至相同程度），而在小脑-桥脑角肿瘤中，W3比W2受到更严重的影响。W1波从未改变。2例患者的术前和术后记录显示肿瘤切除后反应明显改善。在9名患有“特发性”三叉神经痛的患者中，发现疼痛侧的传导延迟，这表明三叉神经根可能在其进入脑桥的入口区受到损伤。对38例三叉神经痛患者中的12例进行了三叉神经半月后注射甘油治疗。手术侧刺激9例W2、W3消失，2例W1-W3间期延长，1例无改变。反应改变的程度通常会影响临床结果。
Early scalp responses evoked by stimulation of the infraorbital nerve (W1, W2, W3) have been investigated in 23 patients affected by tumours of the base of the skull (parasellar area and cerebello-pontine angle) and in 38 patients suffering from ''idiopathic'' trigeminal neuralgia. Differences in conduction times between healthy and affected side were evaluated and confronted with data obtained from 30 normal volunteers. Alterations of the response were found in all the patients with tumours of the base of the skull who had clinical signs in the trigeminal area and in 7 of the 12 cases without such signs. The usual pattern of alteration in cases with tumours of the parasellar area was a parallel involvement of W2 and W3 (both absent or delayed to the same extent), whereas in tumours of the cerebello-pontine angle W3 was more seriously affected than W2. Wave W1 was never altered. Pre- and post-operative recording sessions in 2 patients showed definite improvement of the responses after removal of the tumour. In 9 patients suffering from ''idiopathic'' trigeminal neuralgia delays of conduction were found on the painful side, suggesting that damage to the trigeminal root, possibly at its entry zone into the pons, had taken place. Retrogasserian injection of glycerol was performed in 12 of the 38 patients with trigeminal neuralgia. Stimulation of the operated side showed disappearance of W2 and W3 in 9 cases, prolonged W1-W3 interval in 2 cases and no alterations in 1 case. The extent of response alteration usually paralleled the clinical results.