Synthesis and properties of a temperature-sensitive hydrogel based on physical crosslinking via stereocomplexation of PLLA-PDLA.
Synthesis and properties of a temperature-sensitive hydrogel based on physical crosslinking via stereocomplexation of PLLA-PDLA.
复制标题
基于 PLLA-PDLA 立体络合物理交联的温敏水凝胶的合成与性能
作者：
A synthetic route to amphiphilic conetwork (APCN) gels was developed and involved (1) a ring-opening polymerization (ROP) synthesis of the macromonomer HEMA-PLLA/PDLA, and (2) a radical polymerization of a stereocomplex of the synthesized macromonomers with P(MEO2MA-co-OEGMA) to form the APCN gels. The structure of the gel was successfully verified using X-ray diffraction. Thermal analysis and differential scanning calorimetry data showed that the thermal behaviors of the gels were greatly improved compared with that of polylactic acid (PLA). The mechanical properties of the gels were measured by using a dynamic viscometer, and the results indicated a greater mechanical strength before swelling than afterwards, and an increasing strength of the gels with increasing amount of PLA stereocomplex. Gels placed in different aqueous phases at different temperatures showed different swelling ratio (SR) values. Specifically, the SR gradually decreased as the temperature was increased, indicating a temperature sensitivity of the gels. In addition, the gels placed in the aqueous and organic phases presented as hydrogels and hydrophobic gels, respectively, and their SR values were relatively low. These results indicated the amphiphilic nature of the gel, and indicated great application prospects for the gel in biomedicine.
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影响因子：
5.5
作者：
Lin, Caiping;Gitsov, Ivan
通讯作者：
Gitsov, Ivan
影响因子：
5.5
作者：
Kali, Gergely;Vavra, Szilvia;Ivan, Bela
通讯作者：
Ivan, Bela
影响因子：
5.5
作者：
Lutz, Jean-Francois;Weichenhan, Katja;Hoth, Ann
通讯作者：
Hoth, Ann
影响因子：
5.5
作者：
Domjan, Attila;Fodor, Csaba;Suevegh, Karoly
通讯作者：
Suevegh, Karoly
二嵌段和三嵌段聚乳酸/聚乙二醇共聚物混合的热响应性立体复合水凝胶的原位形成和凝胶化机制
影响因子：
3.3
作者：
Mao, Hailiang;Pan, Pengju;Bao, Yongzhong
通讯作者：
Bao, Yongzhong