Top hat wound configuration for penetrating keratoplasty using the femtosecond laser - A laboratory model
Top hat wound configuration for penetrating keratoplasty using the femtosecond laser - A laboratory model
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DOI：
10.1097/01.ico.0000179739.31196.e8
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发表时间：
2006-04-01
期刊：
影响因子：
2.8
通讯作者：
Sarayba, MA
中科院分区：
文献类型：
--
作者：
Ignacio, TS;Nguyen, TB;Sarayba, MA
目的：为了评估机械稳定性和诱导散光的修改后的多平面“礼帽”伤口配置的全层穿透性角膜移植术（PK）使用飞秒激光相比，PK在实验室model.Methods：8人角巩膜轮辋安装在人工前房。将4份样本分配至传统PK组。四个样本使用飞秒激光进行了全层角膜移植术：从前房到基质中进行9.0 mm的圆柱形切口，然后在角膜深度的三分之二处进行环形（外径9.0 mm，内径7.0 mm）水平板层切除术，并从板层到角膜表面进行7.0 mm的圆柱形切口。机械稳定性进行了评价后放置的基本缝线和运行suture.Results：在“礼帽”PK组，伤口渗漏发生在19 3.36毫米汞柱放置的基本缝线和86.25 +/- 9.74毫米汞柱放置的运行suture. Results后。在传统PK组中，放置主缝线和连续缝线后分别在0 0 mm Hg和76. 25 +/-20. 98 mm Hg下发生渗漏。两种技术均诱导术后角膜曲率变陡。改良伤口组的平均K值平均变化为3.43 +/- 3.62 D，而传统PK组的平均K值平均变化为3.21 +/- 6.67 D。结论：发现飞秒激光产生的PK“礼帽”伤口配置比传统方法产生的伤口配置更具机械稳定性。
Purpose: To evaluate the mechanical stability and induced astigmatism of a modified multiplanar "top hat" wound configuration for full-thickness penetrating keratoplasty (PK) using the femtosecond laser as compared with PK in a laboratory model.Methods: Eight human corneoscleral rims were mounted on an artificial anterior chamber. Four samples were assigned to the traditional PK group. Four samples underwent full-thickness keratoplasty with the femtosecond laser: a 9.0-mm cylindrical cut was made from the anterior chamber into the stroma, followed by a ring-shaped (outer diameter 9.0 mm, inner diameter 7.0 mm) horizontal lamellar resection at two-thirds corneal depth and a 7.0-mm cylindrical cut from the lamellae to the corneal surface. Mechanical stability was evaluated after placement of the cardinal sutures and the running sutures.Results: In the "top hat" PK group, wound leakage occurred at 19 3.36 mm Hg after placement of the cardinal sutures and at 86.25 +/- 9.74 mm Hg after placement of the running sutures. In the traditional PK group, leakage occurred at 0 0 mm Hg and 76.25 +/- 20.98 mm Hg after placement of the cardinal sutures and running sutures, respectively. Both techniques induced steepening of the corneal curvature postop. The modified wound group showed a mean change in average K of 3.43 +/- 3.62 D, whereas the traditional PK group showed a mean change in average K of 3.21 +/- 6.67 D.Conclusion: The femtosecond laser-produced "top hat" wound configuration for PK was found to be more mechanically stable than that produced by the traditional method.