Chemical and Biological Sensor Standards Study

Chemical and Biological Sensor Standards Study
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化学和生物传感器标准研究

DOI:
10.21236/ada458370
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发表时间:
2005
影响因子:
11.4
通讯作者:
J. Carrano
J. Carrano
中科院分区:
医学2区
文献类型:
--
作者:
J. Carrano

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摘要:国防部(DoD)迫切需要开发用于早期预警和保护军事部队免受潜在的化学和生物(C/B)攻击的传感器。不幸的是,用于评估C/B传感器的当前标准和协议是不充分的;并且,这种不充分阻碍了新传感器的开发以及当前传感器的正确评估。为了解决这些缺点,需要一组传感器度量和测量协议,通过它们可以正确地判断C/B传感器的功效。经过简化的弱点和威胁分析,研究发现,C/B传感器所需的灵敏度存在极大的不确定性。所需检测灵敏度的这种不确定性强烈地表明,对于C/B试剂检测,不存在单一理想的传感器灵敏度,并且取决于可接受的假阳性率和其他传感器属性,具有广泛不同灵敏度能力的不同传感器在防御C/B试剂中可能具有有用的作用。除了确定C/B传感器指标和测量协议,研究小组产生了五个关键的发现,这是:1。传感器测试和表征不充分。2.潜在威胁的动态范围很广(浓度> 10(实验5))。3. ROC曲线对于传感器开发、测试和评估至关重要。4.传感器应允许多种操作模式。5.传感器要求没有明确定义。本报告详细介绍了这些主要调查结果,并提出了后续建议。
Abstract : The Department of Defense (DoD) has an urgent need for the development of sensors for early warning and protection of military forces against potential chemical and biological (C/B) attacks. Unfortunately, the current standards and protocols used to evaluate C/B sensors are not adequate; and, this inadequacy hampers the development of new sensors as well as the proper evaluation of current sensors. In order to address these shortcomings, there is a need for a set of sensor metrics and measurement protocols by which the efficacy of C/B sensors can be properly judged. Following a simplified vulnerability and threat analysis, the Study found that there is an extremely large uncertainty in the required sensitivity for C/B sensors. This uncertainty in the required detection sensitivity strongly suggests that there is not a single ideal sensor sensitivity for C/B agent detection and that, depending on the acceptable false positive rates and other sensor attributes, different sensors with widely different sensitivity capabilities may have useful roles in the defense against C/B agents. In addition to identifying C/B sensor metrics and measurement protocols, the Study Panel produced ve key findings, which are: 1. Sensor testing and characterization is inadequate. 2. Potential threats span a very wide dynamic range (> 10 (exp 5) in concentration). 3. ROC curves are essential for sensor development, testing and evaluation. 4. Sensors should allow for multiple operating modes. 5. Sensor requirements are not well defined. The report details these key findings and makes subsequent recommendations.