Oral squamous-cell carcinoma within a white-sponge nevus.
Oral squamous-cell carcinoma within a white-sponge nevus.
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白色海绵痣内的口腔鳞状细胞癌。
DOI：
10.1111/j.1524-4725.1978.tb00476.x
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
R. Plezia
中科院分区：
文献类型：
--
作者：
T. Downham;R. Plezia
1例59岁女性，双侧舌上有厚厚的白斑。这种情况最初是通过活检诊断为白色海绵状雀斑。两年后，对右侧可疑区域进行了第二次活组织检查，显示为鳞状细胞癌。据推测，激素依赖型内源性哮喘的泼尼松治疗可能导致失去了“免疫监测”，这使得之前良性状态下的恶性发展成为可能。
A 59-year-old woman had thick plaques of leukoplakia on the tongue bilaterally. The condition was initially diagnosed by biopsy as a white-sponge nevus. A second biopsy of a suspicious area on the right side showed squamous-cell carcinoma two years later. It is speculated that prednisone therapy for steroid-dependent intrinsic asthma may have caused a loss of "immunologic surveillance," which permitted development of malignancy in a previously benign condition.