Some new aspects of 17α-estradiol metabolism in man
Some new aspects of 17α-estradiol metabolism in man
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DOI：
10.1016/s0039-128x(02)00058-2
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发表时间：
2002-10-01
期刊：
影响因子：
2.7
通讯作者：
Zimmermann, H
中科院分区：
文献类型：
--
作者：
Hobe, G;Schön, R;Zimmermann, H
17alpha-Estradiol (1,3,5(10)-estratriene-3,17alpha-diol) together with a tracer dose of the tritium-labeled compound was administered orally and sublingually to male volunteers. The serum concentrations of 17alpha-estradiol (free and liberated by enzymatic hydrolysis) were quantified by GUMS, and the serum total radioactivity and urinary radioactivity excretion were determined.After oral administration, 17alpha-estradiol was rapidly and intensively conjugated; only tiny quantities of the free steroid (
