Determining Cardiac Fiber Orientation Using FSL and Registered Ultrasound/DTI volumes.
Determining Cardiac Fiber Orientation Using FSL and Registered Ultrasound/DTI volumes.
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使用 FSL 和配准超声/DTI 体积确定心纤维方向。
DOI：
10.1117/12.2217296
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发表时间：
2016
期刊：
影响因子：
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通讯作者：
Fei,Baowei
中科院分区：
文献类型：
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作者：
Dormer,James;Qin,Xulei;Shen,Ming;Wang,Silun;Zhang,Xiaodong;Jiang,Rong;Wagner,MaryB;Fei,Baowei
从弥散张量成像中准确提取心脏纤维方向对于确定心脏结构和功能具有重要意义。然而，磁共振（MR）扩散张量图像的采集是昂贵且耗时的。相比之下，心脏超声成像是快速和相对便宜的，但它缺乏直接测量纤维取向的能力。为了从超声数据创建详细的心脏模型，具有已知纤维取向的三维（3D）扩散张量成像（DTI）可以通过几何掩模被配准到超声体积。在配准之后，可以使用可变形变换场将来自模板DTI的心脏取向映射到心脏。这个过程很大程度上取决于从DTI中准确提取纤维取向。在这项研究中，我们使用FMRIB软件库（FSL），以确定心脏纤维方向的扩散加权图像。对于超声和MRI体积之间的配准，我们实现了81.6± 2.1%的平均Dice相似系数（DSC）。对于从所提出的方法估计纤维方向，与DTI的直接测量相比，我们实现了22.7±3.1°的锐角误差（AAE）。这项工作提供了一种新的方法来产生心脏纤维的方向，可用于许多心脏的应用。
Accurate extraction of cardiac fiber orientation from diffusion tensor imaging is important for determining heart structure and function. However, the acquisition of magnetic resonance (MR) diffusion tensor images is costly and time consuming. By comparison, cardiac ultrasound imaging is rapid and relatively inexpensive, but it lacks the capability to directly measure fiber orientations. In order to create a detailed heart model from ultrasound data, a three-dimensional (3D) diffusion tensor imaging (DTI) with known fiber orientations can be registered to an ultrasound volume through a geometric mask. After registration, the cardiac orientations from the template DTI can be mapped to the heart using a deformable transformation field. This process depends heavily on accurate fiber orientation extraction from the DTI. In this study, we use the FMRIB Software Library (FSL) to determine cardiac fiber orientations in diffusion weighted images. For the registration between ultrasound and MRI volumes, we achieved an average Dice similarity coefficient (DSC) of 81.6±2.1%. For the estimation of fiber orientations from the proposed method, we achieved an acute angle error (AAE) of 22.7±3.1° as compared to the direct measurements from DTI. This work provides a new approach to generate cardiac fiber orientation that may be used for many cardiac applications.