An fMRI version of the Farnsworth-Munsell 100-Hue test reveals multiple color-selective areas in human ventral occipitotemporal cortex
An fMRI version of the Farnsworth-Munsell 100-Hue test reveals multiple color-selective areas in human ventral occipitotemporal cortex
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DOI：
10.1093/cercor/9.3.257
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发表时间：
1999-04-01
期刊：
影响因子：
3.7
通讯作者：
DeYoe, EA
中科院分区：
文献类型：
--
作者：
Beauchamp, MS;Haxby, JV;DeYoe, EA
对脑性色觉障碍患者的研究表明，枕颞叶腹侧皮质对颜色知觉很重要。我们创造了一种临床测试的功能磁共振成像(FMRI)版本，通常用于评估色觉障碍，即Farnsworth-Munsell 100-Hue测试。这项测试要求正常受试者使用视觉刺激中的颜色信息来执行颜色排序任务。需要按亮度排序的测试的修改被用作控制任务。受试者在被动地观看有色刺激时也会被成像。少数区域对彩色刺激的反应大于非彩色刺激，包括初级视觉皮质。颜色选择活动主要集中在枕颞叶腹侧皮质。腹侧皮质的几个区域被识别出来。最后部位于后方梭形回，对应于被动观看有色刺激所激活的区域。侧沟和梭形回有较多的前部和内侧颜色选择区域。这些更多的前部区域在以前使用被动观察有色刺激的成像研究中没有被识别出来，在我们的研究中，当视觉颜色信息与行为相关时，这些区域最活跃，这表明注意力影响颜色选择区域的活动，fMRI版本的Farnsworth-Munsell测试可能在色盲的研究中有用。
Studies of patients with cerebral achromatopsia have suggested that ventral occipitotemporal cortex is important for color perception. We created a functional magnetic resonance imaging (fMRI) version of a clinical test commonly used to assess achromatopsia, the Farnsworth-Munsell 100-Hue test. The test required normal subjects to use color information in the visual stimulus to perform a color sequencing task. A modification of the test requiring ordering by luminance was used as a control task. Subjects were also imaged as they passively viewed colored stimuli. A limited number of areas responded more to chromatic than achromatic stimulation, including primary visual cortex. Most color-selective activity was concentrated in ventral occipitotemporal cortex. Several areas in ventral cortex were identified. The most posterior, located in posterior fusiform gyrus, corresponded to the area activated by passive viewing of colored stimuli. More anterior and medial color-selective areas were located in the collateral sulcus and fusiform gyrus. These more anterior areas were not identified in previous imaging studies which used passive viewing of colored stimuli, and were most active in our study when visual color information was behaviorally relevant, suggesting that attention influences activity in color-selective areas, The fMRI version of the Farnsworth-Munsell test may be useful in the study of achromatopsia.