Patient Perspectives Associated with Intended Duration of Buprenorphine Maintenance Therapy
Patient Perspectives Associated with Intended Duration of Buprenorphine Maintenance Therapy
复制标题
DOI：
10.1016/j.jsat.2015.04.002
复制
发表时间：
2015-09-01
影响因子：
3.9
通讯作者：
Book, Sarah W.
中科院分区：
文献类型：
--
作者：
Bentzley, Brandon S.;Barth, Kelly S.;Book, Sarah W.
阿片类药物使用障碍患者经常过早停止阿片类药物维持治疗（OMT），减少保留并可能限制OMT的疗效。目前的研究是一项对丁丙诺啡维持治疗（BMT）患者（N = 69）的横断面调查。我们检查了患者的人口统计学资料、BMT特征（例如，剂量、BMT时间）以及患者对BMT预期持续时间的看法。此外，还调查了患者继续或停止BMT的原因。结果显示，大多数（82%）参与者报告希望继续BMT至少12个月。首次用药的年龄、BMT时间、对疼痛的关注和对复发的关注都与BMT的预期持续时间呈正相关。以下与BMT的预期持续时间呈负相关：最近与治疗提供者讨论BMT停药，之前尝试停止BMT，对戒断症状的担忧，服用丁丙诺啡的愉快影响，以及BMT与生活，工作或学校义务的冲突。想要继续BMT的最常见原因包括对戒断症状，复发和疼痛的担忧。虽然是初步的，但研究结果突出了患者对BMT的看法的关键问题。本研究的结果提供了可能有助于改善OMT计划和治疗结果的信息。(C)2015 Elsevier Inc. All rights reserved.
Patients with opioid use disorders frequently discontinue opioid maintenance therapy (OMT) prematurely, reducing retention and possibly limiting the efficacy of OMT. The current study is a cross-sectional survey of patients (N = 69) enrolled in buprenorphine maintenance therapy (BMT). We examined patient demographics, BMT characteristics (e.g., dose, time in BMT), and patient perspectives regarding intended duration of BMT. In addition, patients' reasons for continuing or discontinuing BMT were investigated. Results revealed that the majority (82%) of participants reported wanting to continue BMT for at least 12 months. Age at first drug use, time in BMT, concern about pain, and concern about relapse were all positively associated with intended duration of BMT. The following were negatively associated with intended duration of BMT: recent discussion with a treatment provider about BMT discontinuation, prior attempt to discontinue BMT, concern about withdrawal symptoms, experiencing pleasurable effects from taking buprenorphine, and perceived conflicts of BMT with life, work, or school obligations. The most common reasons for wanting to continue BMT included concerns about withdrawal symptoms, relapse, and pain. Although preliminary, the findings highlight key issues with regard to patients' perspectives of BMT. The results of this study provide information that may be useful in improving OMT programs and treatment outcomes. (C) 2015 Elsevier Inc. All rights reserved.