Summary, conclusions and recommendations: adverse temperature levels in the human body
Summary, conclusions and recommendations: adverse temperature levels in the human body
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DOI：
10.1080/0265673031000090701
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发表时间：
2003-05-01
影响因子：
3.1
通讯作者：
Kheifets, L
中科院分区：
文献类型：
--
作者：
Goldstein, LS;Dewhirst, MW;Kheifets, L
2002 年春，世界卫生组织举办的题为“人体不利温度水平”的研讨会汇集了具有热疗生物效应专业知识的科学家，审查数据并确定可用于评估人体暴露于 10-300 GHz 射频 (RF) 电磁辐射的潜在不利影响的证据。该频率范围内的射频暴露标准目前基于热效应。审查了有关热疗对整个身体或身体部分影响生理机能（特别是心脏和循环系统）、诱发其他体温调节反应（如出汗）、影响简单和复杂心理任务的表现、诱发各种热相关疾病（如中暑）和损伤身体组织的能力的信息。考虑了对多种器官的风险。此外，还检查了对发育中的胚胎和胎儿的影响阈值以及可能的致癌作用。这些发现是在细胞和组织对高温的已知细胞和生化反应的背景下讨论的。专家们判断了每项研究的相关性，以便为决策者提供建立安全暴露水平的科学依据。共识是，标准应尽可能考虑温度和暴露时间。
In the spring of 2002, The World Health Organization workshop 'Adverse Temperature Levels in the Human Body' brought together scientists with expertise in biological effects of hyperthermia to review the data and determine the evidence that could be used to evaluate potential adverse effects from human exposures to radiofrequency (RF) electromagnetic radiation in the range of 10-300 GHz. Standards for RF exposure in this frequency range are based currently on thermal effects. Information was reviewed on the ability of hyperthermia, either to the whole body or to part of the body to affect physiology, particularly the heart and circulatory system, to induce other thermoregulatory responses such as sweating, to affect the performance of simple and complex mental tasks, to induce various heat-related disorders such as heat stroke and to damage body tissue. Risks to a variety of organs were considered. In addition, thresholds for effects on developing embryos and foetuses and possible carcinogenic effects were also examined. These findings were discussed in the context of known cellular and biochemical responses of cells and tissues to hyperthermia. The experts judged the relevance of each study for informing decision-makers on the scientific basis for establishing safe exposure levels. The consensus was that standards should consider both temperature and time of exposure, whenever possible.