Effect of antiepileptic drugs on short‐latency somatosensory evoked potentials

Effect of antiepileptic drugs on short‐latency somatosensory evoked potentials
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抗癫痫药物对短潜伏期体感诱发电位的影响

DOI:
10.1111/j.1600-0404.1985.tb03209.x
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发表时间:
1985
影响因子:
3.5
通讯作者:
M. C. Matheshwari
M. C. Matheshwari
中科院分区:
医学3区
文献类型:
--
作者:
N. Borah;M. C. Matheshwari

文献摘要

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摘要-在开始治疗前,记录了45例新诊断的癫痫病例的短潜伏期体感诱发电位(SEP)。在开始苯妥英、卡马西平和苯巴比妥单药治疗后6周和3个月进行随访记录。监测血清药物水平。初始成分(N20)的振幅和潜伏期均保持不变,与研究期间记录SEP的30名年龄和性别匹配的正常人相同。
ABSTRACT – Short‐latency somato sensory evoked potentials (SEPs) were recorded in 45 freshly diagnosed cases of epilepsy before starting treatment. Follow‐up recordings were made 6 weeks and 3 months after diphenylhydantoin, carbamazipine and phenobarbitone monotherapy were started. Serum drug levels were monitored. Both amplitude and latency of the initial component (N20) remained unchanged and were identical to a group of 30 age‐ and sex‐matched normal individuals in whom SEPs were recorded during the period of study.