Conceptual equivalence and health-related quality of life: an exploratory study in Japanese and Dutch cancer patients
Conceptual equivalence and health-related quality of life: an exploratory study in Japanese and Dutch cancer patients
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DOI：
10.1007/s11136-006-0049-1
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发表时间：
2006-08-01
影响因子：
3.5
通讯作者：
Kaptein, A. A.
中科院分区：
文献类型：
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作者：
Kleijn, W. Chr.;Ogoshi, K.;Kaptein, A. A.
关于西方和日本健康相关生活质量(HR-QOL)概念等价性的研究很少。我们使用西欧(欧洲癌症研究与治疗组织，EORTC-QLQ-C30)和日本(HRQOL-20)问卷来分析日本(n=265)和荷兰(n=174)不同类型癌症患者HR-QOL因素的概念相似性，以及具体症状项与总体HR-QOL的关系。这两个群体都完成了这两项测试。在两组患者中，EORTC-QLQ-C30的总体健康量表与HRQOL-20综合平均分高度相关(r=0.59p<；0.001)，表明概念上的可比性。对EORTC-QLQ-C30各症状项与HR-QOL的相关性进行排序，分析各症状项与HR-QOL的相关性。在日本和荷兰的样本中也观察到了类似的模式。研究结果表明，在日本和荷兰的癌症患者中，HR-QQ-C30在概念上具有相当大的等价性，并且在衡量功能和特定症状的项目方面，EORTC-QLQ-C30在结构和跨文化上具有令人满意的等价性。需要进行纵向研究，以检查特定症状对总体生活质量的影响。
Research into the equivalence of Western and Japanese conceptualizations of health-related quality of life (HR-QOL) is scarce. We used the Western (European Organization for Research and Treatment of Cancer, EORTC-QLQ-C30) and the Japanese (HRQoL-20) questionnaire in order to analyze the conceptual similarity of HR-QOL factors, and the associations between specific symptom items with overall HR-QOL in Japanese (n = 265) and Dutch (n = 174) patients with various types of cancer. Both populations completed both instruments. In both patient groups, the overall health scale of the EORTC-QLQ-C30 correlated highly (r = 0.59; p < 0.001) with the HRQOL-20 composite average score, indicating substantial conceptual comparability. Relationships between all EORTC-QLQ-C30 symptom items with HR-QOL were examined by ranking their correlations with the two overall measures of HR-QOL. Comparable patterns in the Japanese and Dutch samples were observed. The results suggest a considerable conceptual equivalence of HR-QOL in Japanese and Dutch cancer patients, and indicate a satisfactory structural and cross-cultural equivalence for the EORTC-QLQ-C30 with regard to items measuring functioning and specific symptoms. Longitudinal studies are needed to examine the impact of specific symptoms on general quality of life.