Factors related to post-stroke depression during the first 2 weeks after stroke
Factors related to post-stroke depression during the first 2 weeks after stroke
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DOI：
10.1177/0308022620936865
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发表时间：
2020-07-22
影响因子：
1.3
通讯作者：
Tsujino, Akira
中科院分区：
文献类型：
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作者：
Mitsunaga, Wataru;Higashi, Toshio;Tsujino, Akira
引言本研究旨在阐明发病2周内急性卒中患者卒中后抑郁的相关因素。方法88例脑卒中患者根据汉密尔顿抑郁量表评分分为脑卒中后抑郁组（49例）和非脑卒中后抑郁组（39例）。我们评估了卒中严重程度、上肢功能、日常生活活动、额叶/认知功能和冷漠程度。使用ActiGraph GT 9 X Link系统测量活动水平。使用Mann-WhitneyU检验来确定两组之间的差异。还进行了斯皮尔曼等级相关和logistic回归分析。结果脑卒中后抑郁组与非脑卒中后抑郁组在入院和出院时的美国国立卫生研究院卒中量表评分、入院时功能独立性测量运动项目、认知项目和总项目、Fugl-Meyer评定量表评分和冷漠评定量表评分方面差异有统计学意义。Logistic回归分析显示Fugl-Meyer评分与卒中后抑郁相关。结论脑卒中严重程度、瘫痪程度、躯体功能/日常生活活动能力与脑卒中后急性期抑郁相关。我们的研究结果表明，身体损害严重程度的增加与卒中后抑郁风险的增加有关。康复专业人员应专注于在卒中后早期阶段识别卒中后抑郁。
Introduction This study aimed to clarify factors associated with post-stroke depression in patients with acute stroke within 2 weeks of onset. Method Eighty-eight patients with stroke were divided into post-stroke depression (n = 49) and non-post-stroke depression (n = 39) groups based on their Hamilton Depression Rating Scale scores. We evaluated stroke severity, upper limb function, activities of daily living, frontal lobe/cognitive function, and level of apathy. Activity levels were measured using an ActiGraph GT9X Link system. Mann-WhitneyU-tests were used to determine differences between the two groups. Spearman's rank correlation and logistic regression analyses were also performed. Results The post-stroke depression and non-post-stroke depression groups exhibited significant differences in National Institutes of Health Stroke Scale scores at admission and discharge; Functional Independence Measure exercise items, cognitive items, and total items at admission; Fugl-Meyer Assessment scores; and Apathy Rating Scale scores. Logistic regression indicated that Fugl-Meyer Assessment scores were associated with post-stroke depression. Conclusion Stroke severity, paralysis, and physical function/activities of daily living ability are associated with post-stroke depression in the acute phase. Our findings suggest that increases in physical impairment severity are associated with increased post-stroke depression risks. Rehabilitation professionals should focus on identifying post-stroke depression in early post-stroke stages.