CLINICOPATHOLOGICAL STAGING FOR COLORECTAL-CANCER - AN INTERNATIONAL DOCUMENTATION SYSTEM (IDS) AND AN INTERNATIONAL COMPREHENSIVE ANATOMICAL TERMINOLOGY (ICAT)
CLINICOPATHOLOGICAL STAGING FOR COLORECTAL-CANCER - AN INTERNATIONAL DOCUMENTATION SYSTEM (IDS) AND AN INTERNATIONAL COMPREHENSIVE ANATOMICAL TERMINOLOGY (ICAT)
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DOI：
10.1111/j.1440-1746.1991.tb00867.x
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发表时间：
1991-07-01
影响因子：
4.1
通讯作者：
NEWLAND, RC
中科院分区：
文献类型：
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作者：
FIELDING, LP;ARSENAULT, PA;NEWLAND, RC
结直肠癌（CRC）肿瘤分期的目的是帮助定义临床管理，促进医生之间的沟通，为前瞻性研究中治疗结果的分层和分析提供基础，并为患者及其家属提供一些预后信息。 世界胃肠病学、消化内窥镜检查和结肠直肠病大会、结直肠癌分期工作组研究了六种常用系统，以审查其优点和缺点。 尽管得出的结论是没有必要定义新的分期系统，但人们认识到有必要定义一个术语来描述 CRC 传播的完整解剖范围。 此外，我们注意到，还有一些来自临床和病理信息的附加特征，通过适当构建的多变量分析显示了这些特征具有预后意义，并且可以用来制定比解剖肿瘤扩散描述提供的更准确的预后指数。因此，工作组得出了两个主要结论。 首先，应采用标准格式来收集前瞻性研究所需的基本数据，为此我们建议使用“CRC 国际文献系统（IDS）”。 其次，描述了 CRC 中肿瘤扩散的完整解剖范围和残留肿瘤状态的命名法已经被定义并应该被采用，所有当前使用的分期系统都可以从中衍生出来。 我们将此命名法称为“CRC 国际综合解剖术语 (ICAT)”。如果这些建议被采纳，我们预计 CRC 患者治疗结果的记录将会更加清晰，并且前瞻性研究结果的交流也会得到改善。 此外，IDS 和 ICAT 的接受将为通过扩展解剖临床病理学分期信息以包括具有独立预后意义的其他因素来为个体 CRC 患者制定预后指数奠定基础。
The purpose of tumour staging for colorectal cancer (CRC) is to help define clinical management, facilitate communication between physicians, provide a basis for stratification and analysis of treatment results in prospective studies, and provide some prognostic information for patients and their families. The World Congresses of Gastroenterology, Digestive Endoscopy, and Coloproctology, Working Party on staging for CRC studied six commonly used systems to review their strengths and weaknesses. Although it was concluded that defining a new staging system was unnecessary, it was recognized that there is a need to define a terminology to describe the full anatomic extent of spread of CRC. Furthermore, we note that there are several additional features, derived from both clinical and pathology information, which have had prognostic significance shown by appropriately constructed multivariate analyses and which can be used to formulate a more accurate prognostic index than that provided by a description of anatomical tumour spread.Thus the Working Party came to two principal conclusions. First, a standard format should be adopted for the collection of the essential data required for prospective studies, and we recommend the 'International Documentation System (IDS) for CRC' for this purpose. Second, a nomenclature which describes the full anatomical extent of tumour spread and residual tumour status in CRC has been defined and should be adopted, from which all currently used staging systems can be derived. We have called this nomenclature the 'International Comprehensive Anatomical Terminology (ICAT) for CRC'.In the event that these recommendations are adopted, we envision that there will be improved clarity in the documentation of treatment outcome for patients with CRC and improved communication of results derived from prospective studies. Furthermore, an acceptance of IDS and ICAT would set the scene to develop a prognostic index for individual patients with CRC by the expansion of anatomical clinicopathology staging information to include additional factors which have independent prognostic significance.