Two new resveratrol (=5-[(1E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol) tetramers with a tetrahydrofuran ring from Dipterocarpus grandiflorus
Two new resveratrol (=5-[(1E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol) tetramers with a tetrahydrofuran ring from Dipterocarpus grandiflorus
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DOI：
10.1002/hlca.200490046
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发表时间：
2004-01-01
影响因子：
1.8
通讯作者：
Darnaedi, D
中科院分区：
文献类型：
--
作者：
Ito, T;Tanaka, T;Darnaedi, D
从大花龙脑香（Dipterocarpus grandiflorus）茎中分离得到两个新的二苯乙烯四聚体化合物大花酚A（1）和B（2），沿着10个已知的二苯乙烯低聚体化合物和岩白菜素。化合物1和2由4个白藜芦醇（= 5-[（1 E）-2-（4-羟基苯基）乙烯基]苯-1，3-二醇）单元组成，在一个四氢呋喃和两个二氢苯并呋喃的部分结构中有8个不对称碳原子。详细的光谱分析，特别是HMBC和NOESY实验，允许区分1和2的构型。
Two new stilbene tetramers, grandiphenols A (1) and B (2), along with ten known stilbene oligomers and bergenin were isolated from the stem of Dipterocarpus grandiflorus. The structures of 1 and 2 composed of four resveratrol (= 5-[(1E)-2-(4-hydroxyphenyl)ethenyl] benzene-1,3-diol) units had eight asymmetric C-atoms in the partial structures of a tetrahydrofuran and two dihydrobenzofuran moieties. Detailed spectroscopic analyses, especially HMBC and NOESY experiments, allowed to differentiate the configurations of 1 and 2.