Liver transplantation in septuagenarians receiving model for end-stage liver disease exception points for hepatocellular carcinoma: The national experience
Liver transplantation in septuagenarians receiving model for end-stage liver disease exception points for hepatocellular carcinoma: The national experience
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DOI：
10.1002/lt.23385
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发表时间：
2012-04-01
影响因子：
4.6
通讯作者：
Box, Terry
中科院分区：
文献类型：
--
作者：
Schwartz, Jason J.;Pappas, Lisa;Box, Terry
美国当前的肝脏分配政策给予 T2 期肝细胞癌 (HCC) 肝移植候选者优先的终末期肝病模型 (MELD) 评分为 22，无论年龄如何。由于高龄可能预示着任何诊断的移植后全因死亡率的增加，因此本研究的目的是检查老年 HCC 患者与年轻患者的总体移植后生存率。根据器官获取和移植网络数据，比较了 Kaplan-Meier 的 5 年生存率。接受原发性肝移植的受者根据年龄分为不同的队列（
Current liver allocation policy in the United States grants liver transplant candidates with stage T2 hepatocellular carcinoma (HCC) a priority Model for End-Stage Liver Disease (MELD) score of 22, regardless of age. Because advanced age may portend an increase in all-cause mortality after transplantation for any diagnosis, the aim of this study was to examine overall posttransplant survival in elderly patients with HCC versus younger cohorts. Based on Organ Procurement and Transplantation Network data, Kaplan-Meier 5-year survival rates were compared. Recipients undergoing primary liver transplantation were stratified into cohorts based on age (