SPINAL METASTASES - THE OBVIOUS, THE OCCULT, AND THE IMPOSTORS

SPINAL METASTASES - THE OBVIOUS, THE OCCULT, AND THE IMPOSTORS
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DOI:
10.1097/00007632-199001000-00001
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发表时间:
1990-01-01
期刊:
影响因子:
3
通讯作者:
MACNAB, I
MACNAB, I
中科院分区:
医学2区
文献类型:
--
作者:
WONG, DA;FORNASIER, VL;MACNAB, I

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对832例晚期诊断为恶性肿瘤的死亡患者的脊柱进行了大体、显微镜和X线检查,以寻找肿瘤的证据。肿瘤大体和骨质破坏或硬化是明显转移的可靠征象。隐性病变可见大体矢状面,但无法检测到放射学发生在26%的脊柱与确认转移性存款。椎体塌陷不是转移的可靠指标。22%的塌陷不是由肿瘤引起的。总的来说,在36%死于肿瘤疾病的患者中发现转移。虽然大多数转移瘤是明显的,但也有放射学上看不见的隐匿性病变。塌陷的椎骨可能是转移性疾病的伪装者。
Spines from 832 deceased patients with a terminal diagnosis of malignant neoplasm were examined grossly, microscopically and radiographically for evidence of tumor. Gross tumor and bone destruction or sclerosis were reliable signs of obvious metastases. Occult lesions visualized on gross sagittal sections but not detectable radiographically occurred in 26% of spines with confirmed metastatic deposits. Vertebral collapse was not a reliable indicator of metastases. Collapse was not caused by neoplasm in 22% of cases. Overall, metastases were found in 36% of patients dying from neoplastic disease. Although most metastases are obvious, occult lesions not visible radiographically occur. Collapsed vertebra may be impostors simulating metastatic disease.