Rfam: an RNA family database
Rfam: an RNA family database
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DOI：
10.1093/nar/gkg006
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发表时间：
2003-01-01
影响因子：
14.9
通讯作者：
Eddy, SR
中科院分区：
文献类型：
--
作者：
Griffiths-Jones, S;Bateman, A;Eddy, SR
Rfam是代表非编码RNA家族的多序列比对和协方差模型的集合。Rfam可在联合王国的网站上查阅，网址为http：/ / www.桑格。AC. uk/ Software/ Rfam/和美国的http：/ / rfam。武斯特尔edu/.这些网站允许用户针对协方差模型库搜索查询序列，并查看多个序列比对和家族注释。该数据库也可以下载的形式，并在本地搜索使用INFERNAL包（http：/ / infernal.武斯特尔edu/）的数据。Rfam（1.0）的第一个版本包含25个家族，它们在EMBL核苷酸数据库的分类分区中注释了超过50000个非编码RNA基因。
Rfam is a collection of multiple sequence alignments and covariance models representing non- coding RNA families. Rfam is available on the web in the UK at http: / / www. sanger. ac. uk/ Software/ Rfam/ and in the US at http: / / rfam. wustl. edu/. These websites allow the user to search a query sequence against a library of covariance models, and view multiple sequence alignments and family annotation. The database can also be downloaded in at le form and searched locally using the INFERNAL package ( http: / / infernal. wustl. edu/). The first release of Rfam ( 1.0) contains 25 families, which annotate over 50 000 non- coding RNA genes in the taxonomic divisions of the EMBL nucleotide database.