Observations on the fine structure and distribution of presumptive baroreceptor nerves at the carotid sinus
Observations on the fine structure and distribution of presumptive baroreceptor nerves at the carotid sinus
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颈动脉窦假定压力感受神经的精细结构和分布观察
DOI：
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发表时间：
1967
期刊：
影响因子：
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通讯作者：
Osler House
中科院分区：
文献类型：
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作者：
P. M. REESl;Osler House
比较神经纤维计数表明，接受丰富的神经支配的颈动脉分叉的区域在程度上对应于具有薄的和弹性的图尼卡中膜的血管壁的区域。在正常家兔和上级颈神经节切除术和/或Hering神经切断术后，通过电子显微镜检查颈动脉窦壁内的假定压力感受性神经。舌咽（压力感受器）神经末梢要么被剥脱细胞覆盖物，要么被雪旺细胞胞质薄薄覆盖，并且在广泛区域内与至少三种窦壁成分密切相关：与中-外膜边缘的弹性蛋白、与外膜内半部分的胶原蛋白以及与分离的外膜平滑肌细胞的表面。这些肌细胞还接受来自上级颈神经节的终末神经支配。窦图尼卡中膜无神经穿入。外膜肌细胞及其相关的感觉和运动神经的空间排列模拟平滑肌梭，可能构成压力感受器输出的传出控制的形态学基础。
Comparative nerve fiber counts show that the areas of the carotid bifurcation receiving a rich innervation correspond in extent to areas of the vascular wall with a thinned and elastic tunica media. Presumptive baroreceptor nerves within the carotid sinus wall were examined by electron microscopy in normal rabbits and also after superior cervical ganglionectomy and/or Hering's nerve transection. The glossopharyngeal (baroreceptor) nerve terminals are either denuded of a cellular covering or are thinly clothed in Schwann cell cytoplasm, and are intimately related over wide areas to at least three sinus wall components: to elastin at the medio‐adventitial border, to collagen in the inner one‐half of the adventitia, and to the surfaces of isolated adventitial smooth muscle cells. These muscle cells also receive a terminal innervation from the superior cervical ganglion. There is no nervous penetration of the sinus tunica media. The spatial arrangement of the adventitial muscle cells and their associated sensory and motor nerves simulates a smooth muscle spindle, possibly constituting a morphological basis for an efferent control of baroreceptor output.