Interlimb coordination is impaired during walking in persons with Parkinson's disease.
Interlimb coordination is impaired during walking in persons with Parkinson's disease.
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DOI：
10.1016/j.clinbiomech.2012.09.005
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发表时间：
2013-01
期刊：
影响因子：
--
通讯作者：
Hass CJ
中科院分区：
文献类型：
--
作者：
Roemmich RT;Field AM;Elrod JM;Stegemöller EL;Okun MS;Hass CJ
上肢和下肢之间的协调对于提供人体步态的动态稳定性非常重要。虽然有限，但先前的研究表明，帕金森病患者的肢体间协调能力可能受损。我们使用连续分析技术扩展了以前的工作，以提高我们对帕金森病患者步态中肢间协调的理解。18名患有帕金森氏症的成年人和15名健康的老年人在地面上行走，同时进行三维动作捕捉。使用交叉协方差技术评估同侧和对侧肩关节矢状角和髋关节角之间的肢体间协调性。独立样本和配对样本t检验分别比较了帕金森病患者组间和两侧肢体间协调的测量结果。应用Pearson相关性来研究肢体间协调测量与统一帕金森病评定量表中步态、姿势和运动迟缓亚分之间的关联。与健康老年人相比，帕金森病患者的同侧和对侧肢体间协调性降低。受疾病影响更严重的上肢和下肢之间的同侧协调性与步态和姿势的临床评分呈负相关。肢间协调性与运动迟缓的临床测量无显著相关。与健康的老年人相比，帕金森病患者在步态中表现出肢体间协调能力的降低。这些协调性的降低与PD患者步态和姿势的临床意义恶化有关，在未来的步态治疗研究中应该考虑到手臂和腿部运动的协调性。
Coordination between the upper and lower extremities is important to providing dynamic stability during human gait. Though limited, previous research has suggested that interlimb coordination may be impaired in persons with Parkinson’s disease. We extend this previous work using continuous analytical techniques to enhance our understanding of interlimb coordination during gait in persons with Parkinson’s disease. Eighteen adults with Parkinson’s disease and fifteen healthy older adults walked overground while undergoing three-dimensional motion capture. Ipsilateral and contralateral interlimb coordination between the sagittal shoulder and hip angles was assessed using cross-covariance techniques. Independent samples and paired samples t-tests compared measures of interlimb coordination between groups and between sides within the participants with Parkinson’s disease, respectively. Pearson’s correlations were applied to investigate associations between interlimb coordination measures and subscores of gait, posture, and bradykinesia on the Unified Parkinson’s Disease Rating Scale. Ipsilateral and contralateral interlimb coordination was reduced in persons with Parkinson’s disease compared to the healthy older adults. Ipsilateral coordination between the upper and lower extremities more affected by disease was found to be negatively associated with clinical scores of gait and posture. Interlimb coordination was not significantly associated with clinical measures of bradykinesia. Persons with Parkinson’s disease exhibit reduced interlimb coordination during gait when compared to healthy older adults. These reductions in coordination are related to clinically-meaningful worsening of gait and posture in persons with PD and coordination of arm and leg movements should be considered in future research on gait therapy in this population.
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影响因子：
14.5
作者：
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