CAROTENOIDS AS CHEMOPREVENTIVE AGENTS

CAROTENOIDS AS CHEMOPREVENTIVE AGENTS
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DOI:
10.1016/0091-7435(89)90032-7
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发表时间:
1989-09-01
影响因子:
5.1
通讯作者:
KRINSKY, NI
KRINSKY, NI
中科院分区:
医学2区
文献类型:
--
作者:
KRINSKY, NI

文献摘要

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类胡萝卜素色素已被建议作为化学预防剂来降低人类癌症风险。本文综述了类胡萝卜素的功能,并综述了类胡萝卜素抑制致突变、恶性转化和肿瘤形成的实验证据。有人认为,类胡萝卜素的抗氧化功能可以解释它们作为化学预防剂的不同作用。
Carotenoid pigments have been suggested as chemopreventive agents for reducing cancer risk in humans. In this article, the functions of carotenoids are reviewed, and the experimental evidence for carotenoid inhibition of mutagenicity, malignant transformation, and tumor formation is reviewed. It is suggested that the antioxidant function of carotenoids may explain their divergent effects as chemopreventive agents.