Dynamics of movement coordination and tremor during gait in Parkinson's disease
Dynamics of movement coordination and tremor during gait in Parkinson's disease
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DOI：
10.1016/0167-9457(95)00044-5
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发表时间：
1996-04-01
影响因子：
2.1
通讯作者：
Wagenaar, RC
中科院分区：
文献类型：
--
作者：
vanEmmerik, REA;Wagenaar, RC
研究了帕金森氏病患者步态的运动协调性、过渡性和稳定性。通过上下肢相对位相的变化来评价运动协调性的变化，用相对位相的标准差来评价模式的稳定性。对单个肢体振荡器和这些振荡器之间的相对相位进行光谱分析，以评估较低和较高(例如，震颤)频率分量对协调动力学的贡献。5名患者和5名年龄匹配的对照组在电动跑步机上以运动速度作为控制参数时，通过加速度法评估协调性的变化。相对相位变化和稳定性特征显示，上肢和下肢的摆动随着行走速度的变化而逐渐变化，这一发现与Schoner等人的模型预测一致。(1990)关于四足行走模式中的步态变化。帕金森病患者在相对阶段的适应总体上低于对照组，尤其是那些累及上肢的患者。相对相位的频率分析还表明：(A)步行速度的系统性标度可以影响帕金森震颤的主频，(B)相对相位的高阶频率分量可以起到功能性的稳定作用，(C)相对相位功率谱的1/f标度特性可以识别帕金森病对协调动力学的更高限制程度。
Movement coordination, transition and stability aspects of gait in individuals with Parkinson's disease were investigated. Changes in movement coordination were evaluated by means of relative phase changes between upper and lower extremities and stability of patterns by means of the standard deviation of relative phase. Spectroscopic analysis of individual limb oscillators and of the relative phase between these oscillators was used to assess the contribution of lower and higher (e.g., tremor) frequency components on the coordination dynamics. Coordination changes in five patients and five age-matched controls were evaluated by means of accelerometry while movement velocity was manipulated as a control parameter on a motor-driven treadmill. Relative phase changes and stability features showed gradual changes in upper and lower extremity oscillations with walking velocity, a finding consistent with model predictions by Schoner et al. (1990) regarding gait changes in the quadrupedal walking mode. Parkinson's disease patients showed overall less adaptations in relative phase than the control group, especially those involving the upper extremities. Frequency analyses of relative phase also demonstrated that (a) systematic scaling of walking velocity can affect the dominant frequency of Parkinsonian tremor, (b) higher order frequency components in relative phase can play a functional, stabilizing role, and (c) 1/f scaling properties of the relative phase power spectrum can identify the higher degree of constraint on the coordination dynamics in Parkinson's disease.