Sleep problems in early childhood and early onset of alcohol and other drug use in adolescence.
Sleep problems in early childhood and early onset of alcohol and other drug use in adolescence.
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DOI：
10.1097/01.alc.0000121651.75952.39
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发表时间：
2004-04
期刊：
影响因子：
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通讯作者：
M. Wong;K. Brower;H. Fitzgerald;R. Zucker
中科院分区：
文献类型：
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作者：
M. Wong;K. Brower;H. Fitzgerald;R. Zucker
没有关于生命早期睡眠问题与随后饮酒之间关系的前瞻性研究。受成人文献的刺激，将睡眠问题与一些成年人随后发生的酒精使用障碍联系起来，我们研究了儿童早期的睡眠问题是否可以预测青春期酒精和其他药物使用的发生，以及这种关系是否由其他已知的这种关系的预测因子介导，即注意力问题，焦虑/抑郁和儿童晚期的攻击性。本研究是一项正在进行的关于酒精和其他物质使用障碍风险发展的纵向研究的一部分。研究参与者是来自社区招募的高风险家庭样本的257名男孩。母亲对孩子3 ~ 5岁时睡眠问题的评分显著预测了孩子在12 ~ 14岁时早期开始使用酒精、大麻和非法药物，以及早期开始偶尔或经常使用香烟。此外，虽然儿童早期的睡眠问题也可以预测儿童后期的注意力问题和焦虑/抑郁，但这些问题并不能介导睡眠问题与酒精和其他药物使用之间的关系。据我们所知，这是第一项前瞻性研究睡眠问题和早期饮酒之间的关系，这是后期酒精问题和酒精使用障碍风险增加的标志。此外，儿童早期睡眠问题似乎是使用酒精以外药物的一个强有力的标志。对预防早期酒精和其他药物使用的影响进行了讨论。
BACKGROUND No prospective studies exist on the relationship between sleep problems early in life and subsequent alcohol use. Stimulated by the adult literature linking sleep problems to the subsequent onset of alcohol use disorders in some adults, we examined whether sleep problems in early childhood predicted the onset of alcohol and other drug use in adolescence and whether such a relationship was mediated by other known predictors of this relationship, namely, attention problems, anxiety/depression, and aggression in late childhood. METHODS This study is part of an ongoing longitudinal study of the development of risk for alcohol and other substance use disorders. Study participants were 257 boys from a community-recruited sample of high-risk families. RESULTS Mothers' ratings of their children's sleep problems at ages 3 to 5 years significantly predicted an early onset of any use of alcohol, marijuana, and illicit drugs, as well as an early onset of occasional or regular use of cigarettes by age 12 to 14. Additionally, although sleep problems in early childhood also predicted attention problems and anxiety/depression in later childhood, these problems did not mediate the relationship between sleep problems and onset of alcohol and other drug use. CONCLUSIONS This is, to our knowledge, the first study that prospectively examines the relationship between sleep problems and early onset of alcohol use, a marker of increased risk for later alcohol problems and alcohol use disorders. Moreover, early childhood sleep problems seem to be a robust marker for use of drugs other than alcohol. Implications for the prevention of early alcohol and other drug use are discussed.