Impact of transient emotions on functional connectivity during subsequent resting state: A wavelet correlation approach
Impact of transient emotions on functional connectivity during subsequent resting state: A wavelet correlation approach
复制标题
DOI：
10.1016/j.neuroimage.2010.10.021
复制
发表时间：
2011-02-01
期刊：
影响因子：
5.7
通讯作者：
Vuilleumier, Patrik
中科院分区：
文献类型：
--
作者：
Eryilmaz, Hamdi;Van De Ville, Dimitri;Vuilleumier, Patrik
人们对静息大脑活动的功能特性了解甚少，但通常与自我监控和内省过程有关。在这里，我们调查了情绪上的积极信息和消极信息对随后休息时大脑活动的不同影响。我们获得了15名参与者在观看恐惧、快乐和中性电影后休息期间的功能磁共振成像数据。有几个大脑区域在休息时比看电影时更活跃，包括后/前扣带皮层（PCC）。ACC)、双侧岛叶和下顶叶（IPL）。使用小波相关方法和小世界网络分析对不同频段的功能连通性进行了评估。前一种情绪会显著增强前扣带皮层和脑岛的静息活动及其耦合，而前额叶皮层腹内侧与杏仁核的耦合则会选择性地减弱。在更高的频带上，看恐怖电影比看快乐电影的效果更明显。此外，在情绪刺激后，ACC和脑岛的静息活动最初受到抑制，随后随着时间的推移逐渐恢复。情绪不影响IPL的平均活动，但增加了与其他区域的连通性。这些发现揭示了从情绪唤醒中恢复的特定神经回路，并强调了情绪突出环境中默认模式网络的复杂功能动态。(C) 2010爱思唯尔公司版权所有。
The functional properties of resting brain activity are poorly understood, but have generally been related to self-monitoring and introspective processes. Here we investigated how emotionally positive and negative information differentially influenced subsequent brain activity at rest. We acquired fMRI data in 15 participants during rest periods following fearful, joyful, and neutral movies. Several brain regions were more active during resting than during movie-watching, including posterior/anterior cingulate cortices (PCC. ACC), bilateral insula and inferior parietal lobules (IPL). Functional connectivity at different frequency bands was also assessed using a wavelet correlation approach and small-world network analysis. Resting activity in ACC and insula as well as their coupling were strongly enhanced by preceding emotions, while coupling between ventral-medial prefrontal cortex and amygdala was selectively reduced. These effects were more pronounced after fearful than joyful movies for higher frequency bands. Moreover, the initial suppression of resting activity in ACC and insula after emotional stimuli was followed by a gradual restoration over time. Emotions did not affect IPL average activity but increased its connectivity with other regions. These findings reveal specific neural circuits recruited during the recovery from emotional arousal and highlight the complex functional dynamics of default mode networks in emotionally salient contexts. (C) 2010 Elsevier Inc. All rights reserved.