HISTONE 2B CAN BE MODIFIED BY THE ATTACHMENT OF UBIQUITIN
HISTONE 2B CAN BE MODIFIED BY THE ATTACHMENT OF UBIQUITIN
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DOI：
10.1093/nar/8.20.4671
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发表时间：
1980-01-01
影响因子：
14.9
通讯作者：
BONNER, WM
中科院分区：
文献类型：
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作者：
WEST, MHP;BONNER, WM
小鼠和人的组蛋白 2B 可以通过翻译后添加泛素进行修饰。在小鼠 L1210 细胞中，两种 H2B 变体都发生了修饰，但修饰程度仅为 1-1.5%，而 H2A 的修饰程度约为 11%。溴化氰肽的分析表明，泛素附着在组蛋白的 C 末端部分。
Histone 2B in mouse and man can be modified by the post-translational additition of ubiquitin. In mouse L1210 cells, both H2B variants are modified, however only to the extent of 1–1.5% compared with about 11% of H2A. Analysis of cyanogen bromide peptides shows that ubiquitin is attached to the C-terminal part of the histone.