A Sesquiterpene Lactone from Irpex lacteus
A Sesquiterpene Lactone from Irpex lacteus
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来自 Irpexlacteus 的倍半萜内酯
DOI：
10.1007/s10600-020-03047-6
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发表时间：
2020-06-03
影响因子：
0.8
通讯作者：
Liu，Ji-Kai
中科院分区：
文献类型：
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作者：
Ding，Jian-Hai;Li，Zheng-Hui;Liu，Ji-Kai
从担子菌 Irpexlacteus 的培养液中分离出一种新的山松烷倍半萜内酯，命名为 irlactin K (1)。通过广泛的光谱分析确定了新化合物的结构。测试了该化合物对五种人类癌细胞系的细胞毒性以及对 11β-羟基类固醇脱氢酶同工酶的抑制活性。
A new tremulane sesquiterpene lactone, named irlactin K (1), was isolated from the culture broth of the basidiomycete Irpex lacteus. The structure of the new compound was established through extensive spectroscopic analyses. The compound was tested for its cytotoxicity against five human cancer cell lines and for its inhibitory activity against isozymes of 11β-hydroxysteroid dehydrogenases.