Age-related differences in medial prefrontal activation in response to emotional images
Age-related differences in medial prefrontal activation in response to emotional images
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DOI：
10.3758/cabn.8.2.153
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发表时间：
2008-06-01
影响因子：
2.9
通讯作者：
Kensinger, Elizabeth A.
中科院分区：
文献类型：
--
作者：
Leclerc, Christina M.;Kensinger, Elizabeth A.
研究表明，衰老会产生一种“积极效应”，年轻人会专注于负面信息，而老年人则专注于积极信息。为了了解这种效应背后的情绪处理中与年龄相关的变化，目前的fMRI研究比较了年轻人和老年人在观看积极、消极和中性图像时的神经活动。结果表明，在腹内侧前额叶皮层（VMPFC）中，信息激发活动的价态发生了显著的年龄相关逆转。与积极图像相比，消极图像更能激活年轻人的VMPFC，而与消极图像相比，积极图像更能激活老年人的VMPFC。VMPFC是一个与情绪信息处理有关的区域，更具体地说，与情绪产生和情绪调节有关。因此，目前的研究结果表明，VMPFC在这些过程中与年龄相关的变化有助于老年人的“积极效应”。
Research has suggested that aging results in a "positivity effect," with young adults dwelling on negative information, and older adults attending to positive information. In order to understand age-related changes in emotional processing underlying this effect, the present fMRI study compared neural activity in young and older adults as they viewed positive, negative, and neutral images. Results indicated a striking age-related reversal in the valence of information eliciting activity within the ventromedial prefrontal cortex (VMPFC). Negative in comparison with positive images activated the VMPFC more for young adults, whereas positive in comparison with negative images activated the VMPFC more for the older adults. The VMPFC is a region associated with the processing of emotional information, and more specifically, with emotion generation and emotion regulation. Therefore, the present results suggest that age-related changes in these processes implemented by the VMPFC contribute to older adults' "positivity effect.".