Axis I comorbidity in body dysmorphic disorder
Axis I comorbidity in body dysmorphic disorder
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DOI：
10.1016/s0010-440x(03)00088-9
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发表时间：
2003-07-01
影响因子：
7.3
通讯作者：
Phillips, KA
中科院分区：
文献类型：
--
作者：
Gunstad, J;Phillips, KA
虽然近年来对身体畸形恐惧症（BDD）的研究有所增加，但这种疾病的共病性却很少受到经验性的关注。这方面的进一步研究是必要的，因为似乎大多数BDD患者至少有一种共病。本研究调查了293例DSM-IV BDD患者的I轴合并症和合并症的临床相关性，其中175例参与了现象学研究，118例参与了BDD的治疗研究。受试者进行了评估与结构化的临床访谈DSM-III-R（SCID-P）和半结构化的工具，以获得临床相关的信息。共病是常见的，在现象学组和治疗组中，平均有两种以上的终生共病I轴疾病。在这两组中，最常见的终生共病轴I障碍是重度抑郁症、社交恐惧症、强迫症（OCD）和物质使用障碍。社交恐惧症通常在BDD发作之前开始，而抑郁症和物质使用障碍通常在BDD发作之后发展。在许多领域，更多的共病疾病与更大的功能障碍和发病率相关。因此，轴I合并症在BDD患者中很常见，并与显著的功能障碍相关。(C)2003年爱思唯尔公司All rights reserved.
Although research on body dysmorphic disorder (BDD) has increased in recent years, this disorder's comorbidity has received lit-tie empirical attention. Further work in this area is needed, as it appears that most patients with BDD have at least one comorbid disorder. This study examined axis I comorbidity and clinical correlates of comorbidity in 293 patients with DSM-IV BDD, 175 of whom participated in a phenomenology study and 118 of whom participated in treatment studies of BDD. Subjects were evaluated with the Structured Clinical Interview for DSM-III-R (SCID-P) and a semistructured instrument to obtain information on clinical correlates. Comorbidity was common, with a mean of more than two lifetime comorbid axis I disorders in both the phenomenology and treatment groups. In both groups, the most common lifetime comorbid axis I disorders were major depression, social phobia, obsessive compulsive disorder (OCD), and substance use disorders. Social phobia usually began before onset of BDD, whereas depression and substance use disorders typically developed after onset of BDD. A greater number of comorbid disorders was associated with greater functional impairment and morbidity in a number of domains. Thus, axis I comorbidity is common in BDD patients and associated with significant functional impairment. (C) 2003 Elsevier Inc. All rights reserved.