THE BEHAVIOR OF CHICKENS, MICE AND RATS DURING EUTHANASIA WITH CHLOROFORM, CARBON-DIOXIDE AND ETHER
THE BEHAVIOR OF CHICKENS, MICE AND RATS DURING EUTHANASIA WITH CHLOROFORM, CARBON-DIOXIDE AND ETHER
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DOI：
10.1258/002367788780746674
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发表时间：
1988-01-01
影响因子：
2.4
通讯作者：
ALLAN, DJ
中科院分区：
文献类型：
--
作者：
BLACKSHAW, JK;FENWICK, DC;ALLAN, DJ
采用氯仿、二氧化碳和乙醚对鸡、幼龄和成年大鼠以及小鼠进行安乐死评估。恢复了行为模式，以提供有关压力的一些迹象。二氧化碳引起的崩溃更快（11.2 . ±. 0.4 s）比氯仿（18.9 . ±. 0.4 s）或醚（> 60 s）。至于死亡所需的时间，在二氧化碳中的小鼠具有最短的时间（48 ± 10分钟）。10 s）和成熟大鼠具有最长的时间（135 . ±. 10 s）。在氯仿中，唯一的差异是延迟死亡（127 . ±. 10、在鸡在二氧化碳和氯仿中的鸡的行为模式相似，除了在二氧化碳中拍打翅膀，即使在无意识的情况下。氯仿被推荐为更美观地可接受的鸡安乐死。考虑到行为标准，建议将二氧化碳用于大鼠和小鼠的安乐死。乙醚不适合作为安乐死的方法，因为它是危险的，缓慢的行动和刺激性。
Euthanasia of chickens, young and mature rats, and mice was assessed using chloroform, carbon dioxide and ether. Behavioural patterns were recovered to give some indication of the stress involved. Carbon dioxide induced collapse faster (11.2 .+-. 0.4 s) than chloroform (18.9 .+-. 0.4 s) or ether (> 60 s). With regard to the time taken to death, in carbon dioxide mice had the shortest time (48 .+-. 10 s) and mature rats had the longest time (135 .+-. 10 s). In chloroform, the only difference was the delayed onset of death (127 .+-. 10 s) in the chicken. Behavioural patterns were similar for the chicken in carbon dioxide and chloroform, except for wing flapping, even when unconscious, in carbon dioxide. Chloroform is recommended as more aesthetically acceptable for euthanasia of chickens. Carbon dioxide is recommended for the euthanasia of both rats and mice, considering behavioural criteria. Ether is unsuitable as a euthanasia method as it is dangerous, slow acting and an irritant.