Molecular identification of Mycobacterium chimaera as a cause of infection in a patient with chronic obstructive pulmonary disease

Molecular identification of Mycobacterium chimaera as a cause of infection in a patient with chronic obstructive pulmonary disease
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DOI:
10.1016/j.diagmicrobio.2008.12.002
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发表时间:
2009-03-01
影响因子:
2.9
通讯作者:
Iwen, Peter C.
Iwen, Peter C.
中科院分区:
医学4区
文献类型:
--
作者:
Bills, Nathan D.;Hinrichs, Steven H.;Iwen, Peter C.

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本报告描述了一名有慢性阻塞性肺病病史的患者嵌合分枝杆菌感染的病例,其中通过分子方法鉴定了该微生物。 K chimaera 是从新鲜肺组织和仪器阴性的分枝杆菌生长指示剂管肉汤培养物中鉴定出来的。使用内部转录间隔区的序列分析来快速鉴定生长缓慢的非结核分枝杆菌属的效用。显示了传统培养方法不成功的地方。 (c) 2009 Elsevier Inc. 保留所有权利。
This report describes a case of Mycobacterium chimaera infection in a patient with a history of chronic obstructive pulmonary disease where the organism was identified by using molecular methods. K chimaera was identified from fresh lung tissue and from an instrument-negative mycobacterial growth indicator tube broth culture. The utility Of Using sequence analysis of the internal transcribed spacer region for the rapid identification of a slow-growing nontuberculous Mycobacterium spp. where conventional culture methods were not successful was shown. (c) 2009 Elsevier Inc. All rights reserved.