Ethanol-glycerin fixation with thymol conservation: A potential alternative to formaldehyde and phenol embalming
Ethanol-glycerin fixation with thymol conservation: A potential alternative to formaldehyde and phenol embalming
复制标题
DOI：
10.1002/ase.1270
复制
发表时间：
2012-07-01
影响因子：
7.3
通讯作者：
Steinke, Hanno
中科院分区：
文献类型：
--
作者：
Hammer, Niels;Loeffler, Sabine;Steinke, Hanno
需要解剖固定和保存，以防止标本发生自溶和分解。虽然固定是负责自溶和分解的结构的主要抑制，但保守保留了固定状态。虽然甲醛被广泛使用，但它已被列为对人类致癌的物质。为此，开发了一种适当的替代品。本技术报告中描述了乙醇-甘油固定和百里酚保存，并与甲醛和苯酚进行了比较。这种方法的设置，组织质量，财务方面，和健康问题进行了讨论。乙醇甘油固定和麝香草酚保护提供了出色的触觉和视觉组织质量。典型的甲醛和苯酚的影响，如皮肤，气道和眼睛刺激，以及致癌作用，可以避免使用乙醇甘油和百里酚代替。乙醇-甘油固定比甲醛更昂贵，并且需要防爆设施。然而，对健康没有影响及其令人信服的组织质量抵消了这些较高的成本。因此，乙醇-甘油固定和麝香草酚保存提供了一种潜在的替代方案，并补充了已建立的固定技术。通过使用所述方法，可以有效地限制致癌的甲醛和有毒的苯酚的使用。解剖学教育。（c）2012年美国解剖学家协会。
Anatomical fixation and conservation are required to prevent specimens from undergoing autolysis and decomposition. While fixation is the primary arrest of the structures responsible for autolysis and decomposition, conservation preserves the state of fixation. Although commonly used, formaldehyde has been classified as carcinogenic to humans. For this reason, an adequate substitute was developed. Ethanol-glycerin fixation and thymol conservation are described and compared with formaldehyde and phenol in this technical report. The setup, tissue qualities, financial aspects, and health concerns of this method are discussed. Ethanol-glycerin fixation and thymol conservation provide outstanding haptic and optic tissue qualities. Typical formaldehyde and phenol effects, such as skin, airway, and eye irritation, as well as carcinogenic effects, can be circumvented by using ethanol-glycerin and thymol instead. Ethanol-glycerin fixation is more expensive than formaldehyde and requires an explosion-proof facility. However, the absence of health effects and its convincing tissue qualities balance these higher costs. Therefore, ethanol-glycerin fixation and thymol conservation provide a potential alternative and complement established fixation techniques. The use of carcinogenic formaldehyde and toxic phenol can be effectively restricted through the use of the described method. Anat Sci Educ. (c) 2012 American Association of Anatomists.