ACTIVITIES OF THE ENZYMES OF KETONE-BODY METABOLISM IN THE DEVELOPING CHICK
ACTIVITIES OF THE ENZYMES OF KETONE-BODY METABOLISM IN THE DEVELOPING CHICK
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DOI：
10.1016/0305-0491(85)90384-0
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发表时间：
1985-01-01
影响因子：
2.2
通讯作者：
BEIS, A
中科院分区：
文献类型：
--
作者：
BEIS, A
发育中的雏鸡在孵化前和孵化后的血液中酮体的浓度高于成人。心脏、腿和胸肌中的3-氧代辅酶A转移酶和乙酰乙酰辅酶A硫解酶在出壳前后的活性均高于成体。3-羟丁酸脱氢酶的活性在孵化过程中和孵化后不断增加，在所有三个肌肉组织。肝脏中酮体合成酶活性在孵化期和孵化后均呈上升趋势。肝脏可能为发育中的小鸡的肝外组织提供燃料，酮体可能作为燃料在新孵化的鸟的骨骼肌中氧化。
The concentration of ketone bodies in the blood of the developing chick prior to and just after hatching were higher than those found in the adult. The activities of 3-oxo acid-CoA transferase and acetoacetyl-CoA thiolase in the heart, leg and pectoral muscle before and after hatching were higher than those of the adult. The activity of 3-ydroxybutyrate dehydrogenase increased constantly during incubation and after hatching in all three muscle tissues. In the liver the activities of the enzymes of ketone body synthesis increased during incubation and after hatching. The live may provide fuel to the extrahepatic tissues of the developing chick, and ketone bodies could contribute as fuel for oxidation in the skeletal muscle of the newly hatched bird.