PROGRESSIVE RIGHT FRONTOTEMPORAL DEGENERATION - CLINICAL, NEUROPSYCHOLOGICAL AND SPECT CHARACTERISTICS

PROGRESSIVE RIGHT FRONTOTEMPORAL DEGENERATION - CLINICAL, NEUROPSYCHOLOGICAL AND SPECT CHARACTERISTICS
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DOI:
10.1159/000107324
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发表时间:
1993-05-01
期刊:
DEMENTIA
影响因子:
--
通讯作者:
LESSER, IM
LESSER, IM
中科院分区:
其他
文献类型:
--
作者:
MILLER, BL;CHANG, L;LESSER, IM

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本文报告5例进行性右半球变性患者的行为学、神经心理学和单光子发射计算机体层摄影特点。总的来说,最大程度受累的大脑区域是右额叶和颞叶。精神病、强迫和行为抑制解除是主要的症状,而且往往是首要症状。情感变得平淡,病人似乎变得遥远而遥远。神经心理学测试并没有发现一个一致的模式,有助于本地化的异常,右额颞区。这些患者与那些行为和精神状态通常正常的左额颞叶变性患者形成鲜明对比。这项研究表明,右脑可能是控制社会行为的主要大脑半球。
The behavioral, neuropsychological and single photon emission computerized tomography characteristics of 5 patients with progressive degeneration of the right hemisphere are described. In all, the brain regions with greatest involvement were right-frontal and temporal. Psychosis, compulsions and behavioral disinhibition were the dominant, and often first, symptoms. Affect was flattened and the patients seemed distant and remote. Neuropsychological testing did not reveal a consistent pattern that helped localize the abnormality to the right frontotemporal region. These patients contrast dramatically to those with left frontotemporal degeneration in whom behavior and psychiatric status is often normal. This study suggests that the right hemisphere may be primary for the control of social conduct.