Factors affecting African-American participation in AIDS research.
Factors affecting African-American participation in AIDS research.
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影响非裔美国人参与艾滋病研究的因素。
DOI：
10.1097/00126334-200007010-00014
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发表时间：
2000
期刊：
影响因子：
--
通讯作者：
Ware,WB
中科院分区：
文献类型：
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作者：
Sengupta,S;Strauss,RP;DeVellis,R;Quinn,SC;DeVellis,B;Ware,WB
背景：虽然非裔美国人不成比例地受到艾滋病流行的影响，但他们在艾滋病研究中的代表性不足，特别是在艾滋病临床试验中。本研究探讨了一个多维结构的不信任和其他因素，可能会影响愿意参加艾滋病research.Methods：共301名非洲裔美国人（年龄≥ 18岁）在达勒姆，北卡罗来纳州参加了横断面调查。与参与者进行了20至25分钟的面对面访谈。结构方程模型被用来开发模型，探索不信任和其他因素影响愿意参加艾滋病researchamong African American.Results：不信任是最强的逆预测愿意参加艾滋病临床试验。不信任与参与艾滋病调查和教育干预的意愿没有显著相关。利他主义、促进者/障碍、宗教信仰和经济团体成员资格也与参与艾滋病临床试验的意愿显著相关。只有利他主义是显着相关的愿意参加艾滋病调查和教育interventions.Conclusions：不信任研究机构是一个重要的障碍，招募非裔美国人在艾滋病临床试验。研究人员需要认识到不信任的问题，以便在非洲裔美国人社区进行艾滋病临床试验时制定更好的招募和保留策略。
Background:Although African Americans are disproportionately affected by the AIDS epidemic, they are underrepresented in AIDS research, particularly in AIDS clinical trials. This study examines a multidimensional construct of distrust and other factors that may affect willingness to participate in AIDS research.Methods:A total of 301 African Americans (aged≥ 18 years) in Durham, North Carolina participated in a cross-sectional survey. In-person interviews, 20 to 25 minutes in length, were conducted with participants. Structural equation modeling was used to develop models exploring distrust and other factors affecting willingness to participate in AIDS research among African Americans.Results:Distrust was the strongest inverse predictor of willingness to participate in AIDS clinical trials. Distrust was not significantly associated with willingness to participate in AIDS surveys and educational interventions. Altruism, facilitators/barriers, religiosity, and economic group membership were also significantly associated with willingness to participate in AIDS clinical trials. Only altruism was significantly associated with willingness to participate in AIDS surveys and educational interventions.Conclusions:Distrust about research institutions is a significant barrier to recruiting African Americans in AIDS clinical trials. Issues of distrust need to be acknowledged by researchers to develop better recruitment and retention strategies when conducting AIDS clinical trials in African-American communities.