Microscopic polyangiitis that presented liver dysfunction prior to noted renal manifestations.
Microscopic polyangiitis that presented liver dysfunction prior to noted renal manifestations.
复制标题
显微镜下多血管炎在出现明显的肾脏表现之前出现肝功能障碍。
作者：
T. Nakamoto;M. Yoshikawa;T. Nakatani;Y. Yamane;S. Iwasawa;M. Matsumoto;M. Kawanami;K. Nishimura;S. Ueda;H. Fukui
在显微镜下多血管炎（MPA），肾脏表现是非常常见的首发症状。在这里，我们报告一个MPA的情况下，提出了肝功能障碍之前，注意到肾脏的表现。一名58岁的妇女因发烧8周住院。实验室检查显示碱性磷酸酶和γ-谷氨酰转肽酶明显升高，而血尿素氮和肌酐水平保持正常。虽然明显的肾功能不全，在这种情况下，住院后不久，医生应该意识到各种临床表现的MPA。抗神经元胞浆自身抗体有助于MPA的诊断。
In microscopic polyangiitis (MPA), renal manifestations are very common as first symptoms. Here, we report a case of MPA which presented liver dysfunction prior to noted renal manifestations. A 58-year-old woman was hospitalized because of a fever for 8 weeks. A laboratory examination revealed marked elevation of alkaline phosphatase and gamma-glutamyl transpeptidase, while blood urea nitrogen and creatinine levels remained normal. Although apparent renal dysfunction developed in this case soon after hospitalization, physicians should be aware of the variety of clinical manifestations in MPA. Moreover, antineutrophil cytoplasmic autoantibodies were found to be helpful for diagnosing MPA.
DOI：
--
发表时间：
1996
期刊：
Journal of the American Society of Nephrology : JASN
影响因子：
--
作者：
S. Hogan;P. Nachman;Wilkman As;J. Jennette;R. Falk
通讯作者：
S. Hogan;P. Nachman;Wilkman As;J. Jennette;R. Falk
DOI：
--
发表时间：
1996
期刊：
Journal of the American Society of Nephrology : JASN
影响因子：
--
作者：
P. Nachman;S. Hogan;J. Jennette;R. Falk
通讯作者：
P. Nachman;S. Hogan;J. Jennette;R. Falk
影响因子：
158.5
作者：
FALK, RJ;JENNETTE, JC
通讯作者：
JENNETTE, JC