Bousangine A, a novel C-17-nor aspidosperma-type monoterpenoid indole alkaloid from Bousigonia angustifolia
Bousangine A, a novel C-17-nor aspidosperma-type monoterpenoid indole alkaloid from Bousigonia angustifolia
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Bousangine A，一种来自 Bousigonia angustifolia 的新型 C-17-nor Aspidosperma 型单萜吲哚生物碱
DOI：
10.1016/j.fitote.2020.104491
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发表时间：
2020-04-01
期刊：
影响因子：
3.4
通讯作者：
Zhang, Yu
中科院分区：
文献类型：
--
作者：
Huo, Zong-Qing;Zhao, Qian;Zhang, Yu
Two new monoterpenoid indole alkaloids, bousangines A (1) and B (2), were isolated from the twigs and leaves of Bousigonia angustifolia. Their structures including absolute configurations were elucidated by a combination of MS, NMR, ECD calculation, and single-crystal X-ray diffraction analysis. Bousangine A (1) possessed a rearrangement pentacyclic skeleton derived from aspidosperma-type alkaloids with C-17 degradation. Their antiproliferative activity against several human cancer cell lines were evaluated.
