Preparation, assessment, and comparison of α-chitin nano-fiber films with different surface charges
Preparation, assessment, and comparison of α-chitin nano-fiber films with different surface charges
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不同表面电荷α-甲壳素纳米纤维薄膜的制备、评价及比较
DOI：
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发表时间：
2015
影响因子：
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通讯作者：
Yimin Fan
中科院分区：
文献类型：
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作者：
Yan Zhang;Jie Jiang;Liang Liu;Ke Zheng;Shiyuan Yu;Yimin Fan
通过部分脱乙酰化和2，2，6，6-四甲基哌啶-1-氧基自由基(TEMPO)氧化α-甲壳素，分别制备了带正电荷和带负电荷的甲壳素纳米纤维。速度氧化甲壳素纳米纤维的平均直径和长度分别为14 ± 4.3和190 ± 1 40 nm，部分脱乙酰甲壳素纳米纤维的平均直径和长度分别为6 ± 1.7和320 ± 105 nm。采用40℃干燥法制备了部分脱乙酰化甲壳素纳米纤维膜(DEChN-F)、TEMPO介导型氧化甲壳素纳米纤维膜(TOChN-F)以及由两者组合而成的复合膜(DE-to-Chn-F)，其中DEChN-F、TOChN-F和DE-to-Chn-F的拉伸强度相似，约为90 Mpa；而壳聚糖膜(几丁糖-F)的拉伸强度约为30 Mpa。此外，TOCHN-F和DE-to-Chn-F在210℃有热失重，DEChN-F在280℃有热失重。最后，纤维素酶对甲壳素纳米纤维膜有轻微的降解作用，为甲壳素纳米材料提供了一种新的生物学性能。
Chitin nano-fibers with positive and negative charges have been, respectively, produced from partially deacetylated and 2,2,6,6-tetramethylpiperidine-1-oxyl radical (TEMPO)-mediated oxidized α-chitin. The average diameters and lengths of the TEMPO-oxidized chitin nano-fibers (TOChN) were 14 ± 4.3 and 190 ± 140 nm, respectively, and the average diameters and lengths of the partially deacetylated chitin nano-fibers (DEChN) were 6 ± 1.7 and 320 ± 105 nm, respectively. A partially deacetylated chitin nano-fiber film (DEChN-F), a TEMPO-mediated and oxidized chitin nano-fiber film (TOChN-F), and a composite film (DE-TO-ChN-F) consisting of a combination of the two were prepared by drying the dispersions at 40 °C. The DEChN-F, TOChN-F, and DE-TO-ChN-F all have similar tensile strengths of approximately 90 MPa; however, the chitosan film (Chitosan-F) had a tensile strength of approximately 30 MPa. In addition, TOChN-F and DE-TO-ChN-F have a thermal weight loss at 210 °C, and DEChN-F has a thermal weight loss at 280 °C. DEChN-F was found to have antimicrobial activity with regards to Escherichia coli. Finally, the chitin nano-fiber films could be slightly degraded by cellulase, which provided a novel biological performance of the chitin nano-material.